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Impact of Body Mass Index and Genetics on Warfarin Major Bleeding Outcomes in a Community Setting

Several studies have demonstrated an association between body mass index (BMI) and warfarin therapeutic dose, but none evaluated the association of BMI with the clinically important outcome of major bleeding in a community setting. To address this evidence gap, we conducted a case–control study to evaluate the association between BMI and major bleeding risk among […]

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Dental Surgery and Antiplatelet Agents: Bleed or Die

In patients taking antiplatelet medications who are undergoing dental surgery, physicians and dentists must weigh the bleeding risks in continuing antiplatelet medications versus the thrombotic risks in interrupting antiplatelet medications. Bleeding complications requiring more than local measures for hemostasis are rare after dental surgery in patients taking antiplatelet medications. Conversely, the risk for thrombotic complications […]

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April 2014: Should Patients Stop Antiplatelet Medication before Oral Surgery? (video)

Should patients stop taking antiplatelet therapy when they have dental surgery? “Absolutely not,” says AJM Editor-in-Chief Dr. Joseph S. Alpert. Check out this video and the April 2014 review on this topic. Check out this new study: Dental Surgery and Antiplatelet Agents: Bleed or Die  

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Risk of Falls & Major Bleeds

Risk of Falls and Major Bleeds in Patients on Oral Anticoagulation Therapy In this prospective cohort, patients, who were on oral anticoagulants and who had a high risk of falling, did not have a significantly increased risk of major bleeds. These findings suggest that falling risk is not a valid reason to avoid oral anticoagulants. […]

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March 2012: Warfarin & Bleeding

In this video, AJM Editor-in-Chief Joseph S. Alpert, MD reviews Safety of Arthrocentesis and Joint Injection in Patients Receiving Anticoagulation at Therapeutic Levels in the March 2012 issue of The American Journal of Medicine.

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