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Four Cancers and a Rash: Henoch–Schönlein Purpura

A patient who had a history of 4 primary malignancies developed a rash that is usually seen among children. The 65-year-old man presented with a 2-day history of anasarca, painless skin lesions, and new arthralgias in both hands. He had a previous diagnosis of amyotrophic dermatomyositis, and although he had none of the typical skin […]

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Gynecomastia: Look Beyond the Obvious

A 29-year-old man was referred to our clinic with a 4-week history of a tender predominant left breast enlargement without nipple discharge. He had been practicing bodybuilding regularly for years, but denied taking anabolic androgenic steroids. His past medical history was unremarkable apart from surgical treatment of undescended testes in childhood. His sexual desire and […]

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Screening for Hepatocellular Carcinoma in Patients with Cirrhosis: A Need to Increase Awareness

Hepatocellular carcinoma is the most common primary liver cancer, occurring largely in patients with cirrhosis. The incidence of hepatocellular carcinoma is rising in the US, as is its mortality, making hepatocellular carcinoma one of the leading causes of cancer-related deaths in the country.1 Despite the fact that early detection improves survival in patients with hepatocellular carcinoma, […]

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Hepatocellular Carcinoma Screening Associated with Early Tumor Detection and Improved Survival Among Patients with Cirrhosis in the US

Professional societies recommend hepatocellular carcinoma screening in patients with cirrhosis, but high-quality data evaluating its effectiveness to improve early tumor detection and survival in “real world” clinical practice are needed. We aim to characterize the association between hepatocellular carcinoma screening and early tumor detection, curative treatment, and overall survival among patients with cirrhosis. Methods We […]

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Not Just Skin Deep: Distant Metastases from Cutaneous Squamous Cell Carcinoma

  Cutaneous squamous cell carcinoma is the second most common cancer in the United States and has 5-year recurrence and metastasis rates of 8% and 5%, respectively.1, 2 However, not all cutaneous squamous cell carcinomas are alike, and the size and location of the primary lesion confers a widely variable risk for recurrence and metastasis. Case Summary […]

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