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Lifestyle Risk Factors Increase the Risk of Hospitalization for Sciatica: Findings of Four Prospective Cohort Studies

The purpose of this study is to assess the effects of lifestyle risk factors on the risk of hospitalization for sciatica and to determine whether overweight or obesity modifies the effect of leisure-time physical activity on hospitalization for sciatica. Methods We included 4 Finnish prospective cohort studies (Health 2000 Survey, Mobile Clinic Survey, Helsinki Health […]

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Smoking Cessation: The Urgent Need for Increased Utilization of Varenicline

In the US, cigarette smoking causes 480,000 premature deaths annually, due mainly to a twofold increased risk of cardiovascular disease and a 20-fold increased risk of lung cancer.1 Public health efforts and effective cessation treatments–including behavioral counseling and medications–have decreased US rates to approximately 14%; they are markedly increasing in most developing countries.2 Smoking and the emerging […]

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Menthol-Flavored Cigarettes: Potentially a Strong Trigger of Acute Eosinophilic Pneumonia

Menthol-flavored cigarettes recently have received significant attention. Lower quit rates and higher relapse rates of smoking in people who smoke menthol-flavored cigarettes have been demonstrated.1 Additional disadvantages of menthol cigarettes also might exist. We present a lesson learned from a case we experienced: Menthol cigarette smoking might be a stronger trigger of acute eosinophilic pneumonia compared […]

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Red Wine Prevents the Acute Negative Vascular Effects of Smoking

Moderate consumption of red wine is associated with fewer cardiovascular events. We investigated whether red wine consumption counteracts the adverse vascular effects of cigarette smoking. Methods Participants smoked 3 cigarettes alone or after drinking a titrated volume of red wine. Clinical chemistry, blood counts, plasma cytokine enzyme-linked immunosorbent assays, immunomagnetic separation of CD14+monocytes for gene […]

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A Rare Cause of Multiple Bone Lesions: Metastasis or Not?

  Magnetic resonance imaging (MRI) shows high sensitivity for detecting metastatic bone tumors, but distinguishing metastasis from benign lesions is sometimes difficult. We report a case of hyperplastic hematopoietic bone marrow mimicking metastasis. Different radioisotopes in nuclear imaging clarified multiple bone lesion pathophysiologies. A 59-year-old woman with no medical history presented with a 6-month history […]

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