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Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in perioperative pain management of patients undergoing coronary artery bypass graft surgery. However, the association of periprocedural use of NSAIDs and clinical outcomes after coronary artery bypass graft is understudied. Methods We conducted a retrospective analysis using pooled data from 2 multicenter randomized controlled trials (PREVENT IV [n = […]

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Salt, Tomato Soup, and the Hypocrisy of the American Heart Association

In no uncertain terms did the American Heart Association (AHA)1 condemn a recent study by Mente et al2 in The Lancet: “The findings in this study are not valid” … “a flawed study” … “you shouldn’t use it to inform yourself about how you’re going to eat” read some of the statements in the AHA’s comment. The study in […]

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Training Geriatric Cardiologists for an Aging Population: Time to Get Going

Our society is aging—20% of the US population will be aged more than 65 years by 2030, and the number of the “oldest old,” those aged more than 85 years, will triple by 2050. Cardiovascular disease prevalence increases exponentially with age, and direct costs for cardiovascular care in the United States will exceed $800 billion […]

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Personalized Activity Intelligence (PAI) for Prevention of Cardiovascular Disease

To derive and validate a single metric of activity tracking that associates with lower risk of cardiovascular disease mortality. Methods We derived an algorithm, Personalized Activity Intelligence (PAI), using the HUNT Fitness Study (n = 4631), and validated it in the general HUNT population (n = 39,298) aged 20-74 years. The PAI was divided into three sex-specific […]

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Cardiovascular Risks of Exogenous Testosterone Use Among Men

We sought to evaluate whether exogenous testosterone therapy is associated with increased risk of serious cardiovascular events as compared with other treatments or placebo. Methods Study selection included randomized controlled trials (RCTs) and observational studies that enrolled men aged 18 years or older receiving exogenous testosterone for 3 or more days. The primary outcomes were […]

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