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What’s in a Mass?: Large Native Mitral Valve Mass

After an elective cystectomy, a 77-year-old man developed postoperative atrial fibrillation, resulting in a surprising new finding and a challenging diagnosis. He had no cardiovascular symptoms or cardiac history. The preoperative electrocardiogram was normal. Transthoracic echocardiogram identified a mass on the mitral valve (Figure 1A), new 3+ aortic valve regurgitation, and 2+ mitral valve regurgitation. Left ventricular […]

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doctor testing for blood pressure

Treatment-Resistant Hypertension and Outcomes Based on Randomized Treatment Group in ALLHAT

  Although hypertension guidelines define treatment-resistant hypertension as blood pressure uncontrolled by ≥3 antihypertensive medications, including a diuretic, it is unknown whether patient prognosis differs when a diuretic is included. Methods Participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) were randomly assigned to first-step therapy with chlorthalidone, amlodipine, or lisinopril. At a Year […]

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Longitudinal Patterns of Cardiorespiratory Fitness Predict the Development of Hypertension Among Men and Women

Most of the existing literature has linked a baseline cardiorespiratory fitness or change between baseline and one follow-up measurement of cardiorespiratory fitness to hypertension. The purpose of the study is to assess the association between longitudinal patterns of cardiorespiratory fitness changes with time and incident hypertension in adult men and women. Methods Participants were aged […]

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Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in perioperative pain management of patients undergoing coronary artery bypass graft surgery. However, the association of periprocedural use of NSAIDs and clinical outcomes after coronary artery bypass graft is understudied. Methods We conducted a retrospective analysis using pooled data from 2 multicenter randomized controlled trials (PREVENT IV [n = […]

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Salt, Tomato Soup, and the Hypocrisy of the American Heart Association

In no uncertain terms did the American Heart Association (AHA)1 condemn a recent study by Mente et al2 in The Lancet: “The findings in this study are not valid” … “a flawed study” … “you shouldn’t use it to inform yourself about how you’re going to eat” read some of the statements in the AHA’s comment. The study in […]

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