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Cardiovascular Risks of Exogenous Testosterone Use Among Men

We sought to evaluate whether exogenous testosterone therapy is associated with increased risk of serious cardiovascular events as compared with other treatments or placebo. Methods Study selection included randomized controlled trials (RCTs) and observational studies that enrolled men aged 18 years or older receiving exogenous testosterone for 3 or more days. The primary outcomes were […]

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Mental Health and Cardiovascular Disease

For centuries, the mind–body relationship has been postulated. These findings suggest that depression and anxiety are not simply “in the mind.” They are real illnesses, like any other physical illnesses, and can negatively impact the entire body, including the cardiovascular system. Despite the abundance of investigation and demonstration of a clear relationship between mental health […]

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Resistant Hypertension and the Pivotal Role for Mineralocorticoid Receptor Antagonists: A Clinical Update 2016

Clinical features of resistant hypertension are described, and the importance of several risk factors undergoing clinical investigation and reappraisal are considered in this review. True resistant hypertension must be distinguished from apparent resistant hypertension, of which important causes include medication nonadherence, illicit drug use, and alcoholism. Ambulatory blood pressure monitoring should be considered to rule out […]

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Reduction in Percent LDL Cholesterol or Attained LDL-C Levels or Both?

The role of low-density lipoprotein cholesterol (LDL-C) in the pathophysiology of atherosclerotic cardiovascular disease, which may present as coronary heart disease, stroke, and peripheral arterial disease, has been well documented in several studies. The decrease in LDL-C levels leads to a significant reduction in the risk of atherosclerotic cardiovascular disease. Statins have become the first line […]

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Cardiovascular Disease Prevention in Men with Vascular Erectile Dysfunction

Men with erectile dysfunction may have a greater risk of cardiovascular disease. Assessment of cardiovascular risk, including coronary artery calcium, should be considered in these patients. Vascular erectile dysfunction is a powerful marker of increased cardiovascular risk. However, current guidelines lack specific recommendations on the role that the evaluation of vascular erectile dysfunction should play […]

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