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Coronary Artery Disease Among Postmenopausal Women

  Epidemiological studies have shown a higher risk of cardiovascular mortality associated with early menopause, but the relation between menopausal age and extent of coronary artery disease after menopause is unknown. We assessed the relation between menopausal age and extent of coronary disease in postmenopausal women with an acute coronary syndrome. Methods A prospective study […]

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Triple vs Dual Antithrombotic Therapy in Patients with AF & CAD

Background The role of triple antithrombotic therapy vs dual antithrombotic therapy in patients with both atrial fibrillation and coronary artery disease remains unclear. This study explores the differences in treatment practices and outcomes between triple antithrombotic therapy and dual antithrombotic therapy in patients with atrial fibrillation and coronary artery disease. Methods Using the Outcomes Registry […]

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Warfarin and Vascular Calcification

  The vitamin K antagonist, warfarin, is the most commonly prescribed oral anticoagulant. Use of warfarin is associated with an increase in systemic calcification, including in the coronary and peripheral vasculature. This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP). MGP is a vitamin K-dependent protein that […]

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Postcardiac Injury Syndrome: A Rare Complication of Elective Coronary Angioplasty

Postcardiac injury syndrome conventionally has been described after myocardial infarction or cardiac surgery, but it is an infrequent complication of endovascular procedures. We report an unusual case of postcardiac injury syndrome occurring immediately after elective angioplasty. A 58-year-old man attended our hospital (Northwick Park Hospital) for elective angiography for symptoms of exertional angina. He had […]

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Exercise and Risk of Coronary Artery Disease: The FIT Project

  Exercise treadmill testing was used to compare risk factors for coronary artery disease among those who use and who do not use pulmonary medication. Background In the general population, the exercise treadmill testing variables of lower resting heart rate, higher peak heart rate, and greater fitness have favorable prognosis for mortality. Patients with obstructive […]

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