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Biomarkers for Heart Failure: An Update for Practitioners of Internal Medicine

Abstract Biomarkers have become an integral part of practicing medicine, especially in heart failure. The natriuretic peptides are commonly used in the evaluation of heart failure, but their role extends beyond diagnosis and includes risk stratification and management of heart failure patients. Newer biomarkers have arrived and are becoming part of routine care of heart […]

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Dr. Joseph S. Alpert

Heart Failure with Preserved Ejection Fraction (video)

Heart failure is usually broken down into two categories: heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF). Hospitalizations for both are comparable, but HFpEF hospitalizations are expected to increase in the future. Consequently, there is a need for better treatments for HFpEF patients. In this video, AJM Editor-in-chief […]

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Contemporary Role for Digoxin in Heart Failure

Physicians who see patients with heart failure (HF) with reduced ejection fraction (HFrEF) must deal with these patients’ symptoms of exercise intolerance, fatigue, and congestion that often lead to hospitalization, despite correct application of guideline-recommended life-prolonging therapies. The result is the current cost of $30 billion spent annually for HF hospitalizations alone, and given the […]

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Digoxin and 30-day All-cause Hospital Admission in Older Patients with Chronic Diastolic Heart Failure

New findings from the DIG trial… Abstract Background In the main Digitalis Investigation Group (DIG) trial, digoxin reduced the risk of 30-day all-cause hospitalization in older systolic heart failure patients. However, this effect has not been studied in older diastolic heart failure patients. Methods In the ancillary DIG trial, of the 988 patients with chronic […]

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food

Antioxidants & Heart Failure

Total Antioxidant Capacity of Diet and Risk of Heart Failure: A Population-based Prospective Cohort of Women In this study, total antioxidant capacity was measured to determine any association between dietary antioxidants and heart failure. Researchers found that a healthful diet that is high in antioxidants may help prevent heart failure. Heart failure has many causes, […]

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