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Joseph S. Alpert

Diet Redux: Which Food Type Leads to Heart Attacks?

No topic has been more hotly debated over recent decades than the role of various foods in the development of atherosclerosis. The earliest animal experiments demonstrated that diets rich in fat and cholesterol produced arterial lesions that resembled atherosclerosis in humans.1 Over subsequent decades, a great deal of animal and human research has been performed exploring […]

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Prevalence of Anxiety and Depression Symptoms in Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries

Myocardial infarction with non-obstructive coronary arteries is a working diagnosis for several heart disorders. Previous studies on anxiety and depression in patients with myocardial infarction with non-obstructive coronary arteries are lacking. Our aim was to investigate the prevalence of anxiety and depression among patients with myocardial infarction with non-obstructive coronary arteries. Methods We included 99 […]

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Importance of Genetic Testing in the Diagnosis of Transthyretin Cardiac Amyloidosis

To the Editor: Systemic amyloidosis results from extracellular deposition of fibrillar material derived from aggregation of precursor proteins into insoluble beta-pleated sheets. The most frequently recognized types are due to prolonged inflammation, deposition of immunoglobulin light chains, and accumulation of transthyretin, a tetrameric protein synthesized in the liver. Transthyretin amyloidosis can occur owing to wild-type […]

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doctor uses tablet with patient

Diabetes Mellitus and Cardiogenic Shock Complicating Acute Myocardial Infarction

Diabetes mellitus (diabetes) increases the risk of acute myocardial infarction, which can result in cardiogenic shock. Data on the relation of diabetes and the occurrence and prognosis of cardiogenic shock postacute myocardial infarction are scant. Methods Among the National Inpatient Sample patients aged ≥18 years and hospitalized for acute myocardial infarction during the 2012-2014 period, […]

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Vena Cava Compression Syndrome in Obesity is Reversed by Bariatric Surgery

To the Editor: Obesity is a major public health problem, with a prevalence of 10% to 20% in Western Europe.1 It is a risk factor for arterial hypertension, atherosclerosis, and heart failure.2 In times of rising prevalence in obesity, bariatric surgery offers an effective way to achieve weight loss.2 The indication for bariatric surgery is provided by interdisciplinary […]

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