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Capillary Fragility in Zika Virus Infection

  A 42-year-old Hispanic woman with no known medical history presented to the hospital with subjective fevers, rash, and arthralgias 5 days after returning to the US from Honduras. She reported multiple mosquito bites while abroad and noted that many relatives had similar symptoms over the preceding weeks. On arrival to the Emergency Department, her […]

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woman holding a hot drink

Associations of Coffee, Tea, and Caffeine Intake with Coronary Artery Calcification and Cardiovascular Events

Coffee and tea are 2 of the most commonly consumed beverages in the world. The association of coffee and tea intake with coronary artery calcium and major adverse cardiovascular events remains uncertain. Methods We examined 6508 ethnically diverse participants with available coffee and tea data from the Multi-Ethnic Study of Atherosclerosis. Intake for each was […]

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The Extent of Myocardial Injury During Prolonged Targeted Temperature Management After Out-of-Hospital Cardiac Arrest

  The aim of this study is to evaluate the extent of myocardial injury by cardiac biomarkers during prolonged targeted temperature management of 24 hours vs 48 hours after out-of-hospital cardiac arrest. Methods This randomized Scandinavian multicenter study compares the extent of myocardial injury quantified by area under the curve (AUC) of cardiac biomarkers during […]

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Joseph S. Alpert

How Can We Improve the Management of Patients with Hypertension?

Hypertension continues to be a major health problem in the United States, affecting more than 76 million US citizens. Despite marked improvement in detection and therapy of patients with hypertension over recent decades, substantial morbidity and mortality still occur, especially in the Southeastern United States. Hypertension detection programs are common throughout the country and can […]

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Chest Pain in a 39-Year-Old Man: What Could Be the Underlying Cause?

  A 39-year-old man with unremarkable past medical history, but with a positive family history for coronary artery disease, was admitted to the hospital because of persistent arterial hypertension and sudden-onset chest pain in the mid-substernal region with neck radiation. Assessment Results from physical examination were unremarkable. The 12-lead electrocardiogram and the cardiac biomarkers were […]

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