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Not Just Skin Deep: Distant Metastases from Cutaneous Squamous Cell Carcinoma

  Cutaneous squamous cell carcinoma is the second most common cancer in the United States and has 5-year recurrence and metastasis rates of 8% and 5%, respectively.1, 2 However, not all cutaneous squamous cell carcinomas are alike, and the size and location of the primary lesion confers a widely variable risk for recurrence and metastasis. Case Summary […]

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Transverse Lines of the Nails

Four distinct, transverse, depressed lines (Figure, A) developed on the fingernails of a 73-year-old man with castration-resistant prostate cancer after 4 cycles of docetaxel-based chemotherapy; the lines were parallel and evenly spaced (Beau’s lines). Three transverse white bands (Figure, B) appeared on the fingernails of a 62-year-old woman with recurrent metastatic soft tissue sarcoma after […]

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Doubly Dangerous: Extranodal NK/T-Cell Lymphoma

The patient’s disease was already very advanced when the diagnosis was determined, and a hazardous complication was developing as well. A 63-year-old woman presented with a 2-month history of symmetrical violaceous swelling of the face (Figure 1A). Faint violaceous patches also marked her neck, upper chest, upper back, and both arms (Figure 1B). In addition, she had been […]

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Immunotherapy in Squamous Cell Skin Carcinoma: A Game Changer?

  A 74-year-old white male was diagnosed with squamous cell carcinoma in 2013. Six months after Mohs surgery, he underwent a left superficial parotidectomy, left neck dissection, and excision of the left postauricular lymph node after confirmation of lymphatic spread. Pathology from the left parietal scalp lesion revealed multifocal invasive squamous cell carcinoma. Extranodal tumor […]

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Primary Care Management of Skin Abscesses Guided by Ultrasound

Primary care providers often manage skin abscesses in the outpatient setting. Estimating the size and depth of an abscess, and distinguishing abscess from cellulitis by clinical examination can be challenging due to surrounding firm tissue induration. Definitive treatment of abscess requires incision and drainage, and the approach chosen may be altered by abscess size, depth, […]

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