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Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and Majocchi’s Granuloma

A 27-year-old woman presented for a second opinion with chest pain, dyspnea, and a worsening rash with new pustules. Three weeks before presentation she developed a small rash on her anterior right lower abdomen. After treatment with topical hydrocortisone and mupirocin, oral valganciclovir and clindamycin, the rash increased in size, developed central clearance, and became warm […]

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Painful Violaceous Purpura on a 44-Year-Old Woman

Returning to the fundamentals of our medical training, eliciting a full social history, including the use of illicit drugs, can be the key to making a correct diagnosis. This point is illustrated in the following case. A 44-year-old woman with a past medical history notable for asthma and heroin abuse, presented to the Emergency Department […]

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Systemic Inflammation Gone Awry: PASH Syndrome and Temporomandibular Joint Ankylosis

The development of new symptoms in a patient with hidradenitis suppurativa led to the recognition of a systemic autoinflammatory condition. A long battle with hidradenitis suppurativa and acne became even more difficult for a 24-year-old man who developed increasing pain and malodorous drainage from the chronic subcutaneous nodules on his axillae, groin, and buttocks, as […]

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Rash and Fever: Clues to an Elusive Hematologic Malignancy

In a previously healthy older adult, a generalized rash gave way to an elusive diagnosis. Six weeks before the present hospitalization and after a period of sun exposure, this 65-year-old woman developed a pruritic rash on her arms, legs, and trunk that spared her face, palms, and soles. Shortly thereafter, the rash was followed by […]

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Psoriasis

Treatment of Psoriasis with Mesenchymal Stem Cells

  Psoriasis is an incurable immune-mediated disease, which affects approximately 2% of the world’s population. Current treatments, including newly emerged biologic agents, have some limitations.1 Here, we report 2 cases of psoriasis vulgaris treated by umbilical cord-derived mesenchymal stem cells (UC-MSCs). In these 2 cases, both of the patients remained relapse free for 4 or 5 […]

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