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At the Root: Cutaneous Langerhans Cell Histiocytosis

Hair loss is of deep concern to patients, mainly because of its effect on appearance. On rare occasions, however, areas of balding can signal malignancy. A 33-year-old woman was referred to our dermatology clinic because of a 15-year history of scalp eruption accompanied by intense itching and progressive hair loss. Previously, she was diagnosed with […]

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Koplik’s Spots and Measles

To the Editor: Measles, one of the most transmissible diseases, is most contagious before rash manifestation. Search for the pathognomonic Koplik’s spots could be critical for the early diagnosis in this prodromal period. Case Description A 47-year-old man had high-grade fever with a peak temperature of 39.7°C, photophobia, rhinitis, and dry cough. On the fifth […]

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A Plethora of Pustules: Acute Generalized Exanthematous Pustulosis

The patient’s presentation suggested a number of serious dermatologic or infectious diseases, but in fact, a drug reaction was to blame for her symptoms. A 69-year-old woman with a history of chronic obstructive pulmonary disease was admitted to our hospital with a worsening rash. Four days earlier she presented to a different facility with a […]

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Sweet’s Syndrome Mimicking Anti-Neutrophil Cytoplasmic Antibodies–Associated Vasculitis

  Sweet’s syndrome is a rare neutrophilic skin disorder. The antibodies against neutrophil cytoplasmic antigens are called anti-neutrophil cytoplasmic antibodies (ANCAs). Positivity for ANCA has been reported in some nonvasculitic inflammatory disorders, including Sweet’s syndrome.1, 2 Here we report a case of myeloperoxidase (MPO)-ANCA– and (proteinase 3) (PR3)-ANCA–positive Sweet’s syndrome presenting unusual and severe purpuras. A 41-year-old […]

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Disseminated Zoster After Trauma in an Immunocompetent Patient

  An 88-year-old man presented to the emergency department with dizziness and vesicular lesions in various stages of healing on the right lateral face, right ear, arms, legs, and chest. Incidentally he reported a ground-level fall in which he struck his face 2 days prior. The facial lesions were thought to be cellulitis, and he […]

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