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Sweet’s Syndrome Mimicking Anti-Neutrophil Cytoplasmic Antibodies–Associated Vasculitis

  Sweet’s syndrome is a rare neutrophilic skin disorder. The antibodies against neutrophil cytoplasmic antigens are called anti-neutrophil cytoplasmic antibodies (ANCAs). Positivity for ANCA has been reported in some nonvasculitic inflammatory disorders, including Sweet’s syndrome.1, 2 Here we report a case of myeloperoxidase (MPO)-ANCA– and (proteinase 3) (PR3)-ANCA–positive Sweet’s syndrome presenting unusual and severe purpuras. A 41-year-old […]

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Disseminated Zoster After Trauma in an Immunocompetent Patient

  An 88-year-old man presented to the emergency department with dizziness and vesicular lesions in various stages of healing on the right lateral face, right ear, arms, legs, and chest. Incidentally he reported a ground-level fall in which he struck his face 2 days prior. The facial lesions were thought to be cellulitis, and he […]

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Four Cancers and a Rash: Henoch–Schönlein Purpura

A patient who had a history of 4 primary malignancies developed a rash that is usually seen among children. The 65-year-old man presented with a 2-day history of anasarca, painless skin lesions, and new arthralgias in both hands. He had a previous diagnosis of amyotrophic dermatomyositis, and although he had none of the typical skin […]

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Doubly Dangerous: Extranodal NK/T-Cell Lymphoma

The patient’s disease was already very advanced when the diagnosis was determined, and a hazardous complication was developing as well. A 63-year-old woman presented with a 2-month history of symmetrical violaceous swelling of the face (Figure 1A). Faint violaceous patches also marked her neck, upper chest, upper back, and both arms (Figure 1B). In addition, she had been […]

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Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and Majocchi’s Granuloma

A 27-year-old woman presented for a second opinion with chest pain, dyspnea, and a worsening rash with new pustules. Three weeks before presentation she developed a small rash on her anterior right lower abdomen. After treatment with topical hydrocortisone and mupirocin, oral valganciclovir and clindamycin, the rash increased in size, developed central clearance, and became warm […]

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