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Dipeptidyl Peptidase-4 Inhibitors, Peripheral Arterial Disease, and Lower Extremity Amputation Risk in Diabetic Patients

Recent studies have elucidated the vascular protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitors. However, to date, no large-scale studies have been carried out to determine the impact of DPP-4 inhibitors on the occurrence of peripheral arterial disease, and lower extremity amputation risk in patients with type 2 diabetes mellitus. Methods We conducted a retrospective registry […]

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(A) Comparison of structures of periodontal tissues in health and disease. (B) Measurement of periodontal pocket depth using a periodontal probe. (C) Illustration of measurement method and pathologic landmarks of periodontal diseases. A = alveolar bone; BP = bottom of the periodontal pocket; C = calculus; CAL = clinical attachment loss; CEJ = cemento-enamel junction; D = destructive alveolar bone; E = epithelium; G = gingival sulcus; GR = gingival recession; H = healthy gingiva; I = inflammatory gingiva; P = periodontal pocket; PPD = periodontal pocket depth; PD = periodontal disease; R = root.

Periodontal Pocket Depth, Hyperglycemia, and Progression of Chronic Kidney Disease

No large epidemiological study has been conducted to investigate the interaction and joint effects of periodontal pocket depth and hyperglycemia on progression of chronic kidney disease in patients with periodontal diseases. Methods Periodontal pocket depth was utilized for the grading severity of periodontal disease in 2831 patients from January 2002 to June 2013. Progression of […]

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Coronal (A), sagittal (B), and transverse (C) views of abdominal computed tomography scan with oral contrast reveals large, extensive gas collection that encases the distal stomach, duodenum, and pancreas (*). The collection tracks inferiorly along the bilateral paracolic (**). Liver images demonstrate diffuse hypoattenuation and enlargement consistent with steatosis. Gallbladder is distended. There is no evidence of contrast extravasation from the small bowel or of the gastrointestinal tract. G = gallbladder; L = liver; LK = left kidney; P = pancreas; RK = right kidney; Sp = spleen; St = stomach.

Severe Acute Necrotizing Pancreatitis in a Patient with Diabetic Ketoacidosis

A 43-year-old uninsured man with a history of heavy alcohol abuse was admitted to the hospital with 6 months of malaise, nausea, abdominal distension, and pain. More recently he was experiencing dizziness, weakness, excessive urinary volume, and a nonproductive cough. Approximately four months before presentation he had been diagnosed with diabetes mellitus, but was unable […]

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white rice in a bowl

A Blend of Sesame and Rice Bran Oils Lowers Hyperglycemia and Improves the Lipids

  Considering the health benefits of sesame oil and rice bran oil, the study was conducted to determine the extent to which the daily use of this blend of oils controls hyperglycemia and improves the lipid profile. Methods In this 8-week open-label randomized dietary intervention study, 300 type 2 diabetes mellitus patients and 100 normoglycemic […]

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Changes in Lipid Profile of Obese Patients following Bariatric Surgery (video)

In-depth, multi-study analysis characterizes role of contemporary bariatric surgery procedures in benefiting serum lipids. Fifty years after the first reported partial-ileal bypass, metabolic surgery has an established role in achieving weight loss and reducing cardiovascular death in obese patients. Scientists have now demonstrated that it can significantly benefit the lipid profiles of these patients a […]

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Top 10 Facts to Know About Inpatient Glycemic Control

Optimizing glycemic control should be a priority for all health care providers in the inpatient setting. Uncontrolled hyperglycemia in hospitalized patients with or without a previous diagnosis of diabetes is associated with adverse outcomes and longer lengths of hospital stay. It is estimated that one-third of hospitalized patients will experience significant hyperglycemia, and the cost […]

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