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Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in perioperative pain management of patients undergoing coronary artery bypass graft surgery. However, the association of periprocedural use of NSAIDs and clinical outcomes after coronary artery bypass graft is understudied. Methods We conducted a retrospective analysis using pooled data from 2 multicenter randomized controlled trials (PREVENT IV [n = […]

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close up of gloved hands filling a syringe

Ten Immunization-Related Tips in Outpatient Practice

Keeping up with immunization recommendations and implementing them can be an ongoing challenge for clinicians. Ten tips related to various immunizations given in the outpatient setting are presented, as well as resources useful to the clinician in his or her daily practice. Keeping up with immunization recommendations and implementing them are ongoing challenges for clinicians. […]

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Smoking Cessation: The Urgent Need for Increased Utilization of Varenicline

In the US, cigarette smoking causes 480,000 premature deaths annually, due mainly to a twofold increased risk of cardiovascular disease and a 20-fold increased risk of lung cancer.1 Public health efforts and effective cessation treatments–including behavioral counseling and medications–have decreased US rates to approximately 14%; they are markedly increasing in most developing countries.2 Smoking and the emerging […]

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nurse holding hand of elderly woman patient

Dipeptidyl Peptidase-4 Inhibitors, Peripheral Arterial Disease, and Lower Extremity Amputation Risk in Diabetic Patients

Recent studies have elucidated the vascular protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitors. However, to date, no large-scale studies have been carried out to determine the impact of DPP-4 inhibitors on the occurrence of peripheral arterial disease, and lower extremity amputation risk in patients with type 2 diabetes mellitus. Methods We conducted a retrospective registry […]

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Still Febrile After All These Weeks

A previously healthy 28-year-old man was admitted to an outside hospital with fever, pharyngitis, and diarrhea. His symptoms began with generalized fatigue, fever, night sweats, pharyngitis, diffuse myalgias and arthralgias, and 10-pound weight loss. He self-administered a 5-day course of azithromycin. Afterwards, he developed malodorous and watery diarrhea, abdominal cramping, tenesmus, and incomplete evacuation. On […]

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