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Nonsteroidal Anti-Inflammatory Drugs and Clinical Outcomes in Patients Undergoing Coronary Artery Bypass Surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used in perioperative pain management of patients undergoing coronary artery bypass graft surgery. However, the association of periprocedural use of NSAIDs and clinical outcomes after coronary artery bypass graft is understudied. Methods We conducted a retrospective analysis using pooled data from 2 multicenter randomized controlled trials (PREVENT IV [n = […]

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Harmful Effects of NSAIDs among Patients with Hypertension and Coronary Artery Disease

There is limited information regarding the safety of chronic non-steroidal anti-inflammatory drugs (NSAIDs) in hypertensive patients with coronary artery disease. This research study found that among hypertensive patients with coronary artery disease, chronic self-reported NSAID use over a mean of 2.7 years was associated with a 47% increase in the first occurrence of death, nonfatal […]

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July 2011: NSAIDs & Heart Disease (video)

Do non-steroidal anti-inflammatory drugs (NSAIDs) increase your risk for heart disease? Check out new research in the July 2011 issue of The American Journal of Medicine  For a preview of important research in this issue, check out this video with Editor-in-Chief Joseph S. Alpert, MD.

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Analgesic Use and the Risk of Hearing Loss in Men

Regular use of aspirin, acetaminophen and nonsteroidal anti-inflammatory drugs, the most commonly used drugs in the US, may increase risk of hearing loss in men. Abstract Background Hearing loss is a common sensory disorder, yet prospective data on potentially modifiable risk factors are limited. Regularly used analgesics, the most commonly used drugs in the US, […]

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