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Hypertriglyceridemia-Induced Acute Pancreatitis with Normal Pancreatic Enzymes

To the Editor: The diagnosis of acute pancreatitis requires 2 of the following 3 features: 1) abdominal pain consistent with acute pancreatitis; 2) serum lipase activity (or amylase activity) at least 3 times greater than the upper limit of normal; and 3) characteristic imaging findings of acute pancreatitis.1 Although normal serum amylase levels have been reported […]

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Emphysematous Pancreatitis

A 63-year-old woman with a history of severe alcohol abuse presented with persistent abdominal pain radiating to the back, vomiting, and lassitude over a week. Examination showed tachycardia, abdominal tenderness, and bipedal edema. Abdominal ultrasound demonstrated only fatty liver. Laboratory tests were notable for white blood cell count of 16.1 × 109/L, serum albumin 1.8 g/dL, and increased […]

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Diffuse Cerebral Edema from Acute Pancreatitis Induced by Hypertriglyceridemia

Hypertriglyceridemia is the third most common cause of acute pancreatitis, accounting for up to 4% of cases.1, 2Severe acute pancreatitis is characterized by persistent organ failure for >48 hours and warrants intensive care unit admission because it has a mortality rate of 20%.3 Patients with severe acute pancreatitis have been noted to have higher levels of proinflammatory […]

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