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Appropriate Use of Proton Pump Inhibitors: A Double-Edged Sword

We read with great interest the article published by Wombell et al in the current issue of The American Journal of Medicine. The authors summarize the evidence linking proton pump inhibitors (PPIs) to hospital-acquired Clostridium difficile infection.1 They also provide a description of the possible mechanisms responsible for this association. We commend the authors for their timely contribution to the […]

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Disseminated Zoster After Trauma in an Immunocompetent Patient

  An 88-year-old man presented to the emergency department with dizziness and vesicular lesions in various stages of healing on the right lateral face, right ear, arms, legs, and chest. Incidentally he reported a ground-level fall in which he struck his face 2 days prior. The facial lesions were thought to be cellulitis, and he […]

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Sometimes the Eyes Say More Than the Mouth

A 48-year-old man with a history of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS)-associated cryptococcal meningitis was referred to our hospital with blurred vision in his left eye for several months. He was diagnosed with bilateral chronic posterior uveitis (Figure). After ruling out secondary uveitis, such as sarcoidosis, Behçet disease, Vogt-Koyanagi-Harada disease, […]

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Platelet Count of Zero: A Curious Case of Thrombocytopenia

To read this article in its entirety please visit our website. -Patrick Twohig, MD, MPH, Jaclyn Rivington, MD This article originally appeared in the November 2017 issue of The American Journal of Medicine.

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Post-Polio-Like Syndrome

  Post-polio syndrome is a motor neuron disease that occurs in 15%-80% of patients with a history of polio.1 The diagnostic criteria for post-polio syndrome include a confirmed history of polio, partial or complete neurologic and functional recovery after acute polio, a period of more than 15 years with neurologic and functional stability, new symptoms that […]

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