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Hints of Lyme: Disseminated Borreliosis Involving the Mitral and Tricuspid Valves

A 33-year-old man with cystic fibrosis 220 days removed from bilateral lung transplantation presented with 1 week of intermittent fevers (maximum 102°F), malaise, bilateral lower extremity edema, unintentional weight gain (8 pounds), and 2 days of dyspnea on exertion. His posttransplant course was complicated by persistent leukopenia with intermittent neutropenia attributed to his antirejection regimen of […]

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The Clinical Relevance of Studies on Borrelia burgdorferi Persisters

In North America, Lyme disease is principally caused by Borrelia burgdorferi sensu stricto, hereafter referred to as “B. burgdorferi.” It is acquired by the bite of an infected Ixodes tick. The most common clinical manifestation is a skin lesion, referred to as “erythema migrans,” which is due to cutaneous infection with B. burgdorferi. Other objective manifestations may involve the nervous […]

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False and Misleading Information About Lyme Disease

  Recently, there has been considerable interest in the topic of fake news. For infectious diseases physicians, false and misleading information about the diagnosis and treatment of Lyme disease is not new. It is increasing in frequency and prominence, creating much confusion among primary care physicians and their patients. Persistent, unexplained subjective symptoms such as […]

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Post-Lyme Disease Symptoms Revisited

On the Internet, in the halls of academia, and on self-help television shows, the chronic Lyme disease battle rages on. In March 2013 issue, The American Journal of Medicine published Common Misconceptions About Lyme Disease by Halperin et al. This review– as the title suggests– carefully outlines misconceptions about Lyme disease and explains the research and […]

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March 2013: Lyme Disease

The March 2013 issue of The American Journal of Medicine includes a thorough review of acute and chronic Lyme disease diagnosis and treatment, in addition to explaining some common misconceptions about Lyme disease. In this video, Editor-in-chief Dr. Joseph S. Alpert discusses some of the high points of the article.

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