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Post-Polio-Like Syndrome

  Post-polio syndrome is a motor neuron disease that occurs in 15%-80% of patients with a history of polio.1 The diagnostic criteria for post-polio syndrome include a confirmed history of polio, partial or complete neurologic and functional recovery after acute polio, a period of more than 15 years with neurologic and functional stability, new symptoms that […]

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Case of Tuberculous Pericarditis Mimicking Lupus Carditis

A 48-year-old man presented to the emergency department of our hospital complaining of sharp substernal chest pain, fever, and chills for 3 days. He denied shortness of breath, cough, night sweats, nausea, vomiting, or diarrhea. He also denied dry eyes, dry mouth, oral ulcers, or photosensitivity. He was born in the Dominican Republic but has […]

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Hints of Lyme: Disseminated Borreliosis Involving the Mitral and Tricuspid Valves

A 33-year-old man with cystic fibrosis 220 days removed from bilateral lung transplantation presented with 1 week of intermittent fevers (maximum 102°F), malaise, bilateral lower extremity edema, unintentional weight gain (8 pounds), and 2 days of dyspnea on exertion. His posttransplant course was complicated by persistent leukopenia with intermittent neutropenia attributed to his antirejection regimen of […]

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Not so Obvious: Acute Herpes Esophagitis

  The gross examination immediately suggested infection with Candida species, but biopsy results pointed to a different culprit. A 29-year-old woman sought care in the emergency department after experiencing sharp epigastric pain over 2 days. She was initially seen at an urgent care center and empirically treated for gastritis with omeprazole. However, her pain progressively worsened and […]

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The Clinical Relevance of Studies on Borrelia burgdorferi Persisters

In North America, Lyme disease is principally caused by Borrelia burgdorferi sensu stricto, hereafter referred to as “B. burgdorferi.” It is acquired by the bite of an infected Ixodes tick. The most common clinical manifestation is a skin lesion, referred to as “erythema migrans,” which is due to cutaneous infection with B. burgdorferi. Other objective manifestations may involve the nervous […]

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