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Prevention of Anaphylaxis: The Role of the Epinephrine Auto-Injector

  Anaphylaxis is a life-threatening condition, with at-risk individuals remaining at chronic high risk of recurrence. Anaphylaxis is frequently underrecognized and undertreated by healthcare providers. The first-line pharmacologic intervention for anaphylaxis is epinephrine, and guidelines uniformly agree that its prompt administration is vital to prevent progression, improve patient outcomes, and reduce hospitalizations and fatalities. Healthcare costs […]

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CME: Improving Outcomes Among Asthma Patients

A new American Journal of Medicine continuing education program– Strategies to Improve Outcomes in Patients with Asthma– will provide physicians with imperative information about the rationale of asthma control for each stage of disease. Expert panel will discuss biomarkers of disease activity, new biologics and the asthma and COPD overlap syndrome among other relevant topics. […]

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Long-acting Beta-Agonists with and without Inhaled Corticosteroids and Catastrophic Asthma Events

There is a 3-fold increase in asthma-related intubations and deaths in those taking long-acting beta-agonists with concomitant corticosteroids compared to corticosteroids alone, according to this meta-analysis. Abstract Background It is unclear whether long-acting β-agonists with concomitant inhaled corticosteroids increase asthma-related intubations and deaths. We pooled data on long-acting β-agonists with variable and concomitant inhaled corticosteroids […]

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Comorbidities, Patient Knowledge, and Disease Management in a National Sample of Patients with COPD

Comorbidities are common in chronic obstructive pulmonary disease (COPD) and likely add to the complexity and cost of care. Patient self-knowledge about COPD is lower than for cardiovascular comorbidities. COPD is undertreated compared with generally asymptomatic, less morbid conditions such as hypertension. Abstract Objective COPD is the fourth leading cause of death in the United […]

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