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Fabry Disease: An Uncommon Cause of Renal Failure

To the Editor: Fabry disease is an X-linked disorder caused by glycosphingolipid accumulation due to α-galactosidase (GLA) deficiency. Data are limited in patients with Latin American ancestry. We present the case and genetics of a late-diagnosed Fabry disease patient who presented with end-stage renal disease. Case Report A 30-year-old Mexican man without known medical conditions […]

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Life with One Kidney: Primary Care and the Living Kidney Donor

Living donor kidney transplantation is an excellent option for those with end-stage renal disease, and there have been 133,000 living donors in the US since 1988.1 Donor nephrectomy is considered low-risk surgery, with a perioperative mortality of 0.03% and few major complications. Donors generally fare well after nephrectomy, with most studies showing no increase in long-term […]

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Angiotensin Receptor Blockers: Current Status and Future Prospects

Angiotensin receptor blockers (ARBs), through their physiological blockade of the renin-angiotensin system, reduce morbidity and mortality associated with hypertension, heart failure, myocardial infarction, stroke, diabetic nephropathy, and chronic kidney disease. The author reviews results from multiple clinical trials of ARBs. Abstract Angiotensin receptor blockers (ARBs), through their physiological blockade of the renin-angiotensin system, reduce morbidity […]

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Do Income Level and Race Influence Survival in Patients Receiving Hemodialysis?

Hemodialysis patients residing in lower- vs. higher income areas have lower mortality rates, are younger, and more frequently African-American. After adjustment for demographic, clinical, provider, and socioeconomic status characteristics, mortality is similar across income areas. Adjustment for race masks lower mortality in African-Americans. Abstract Background Residence in a lower-income area has been associated with higher […]

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