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Trends and Disparities in Osteoporosis Screening Among Women in the United States, 2008-2014

The United States Preventive Services Task Force recommends universal osteoporosis screening among women ages 65+ and targeted screening of younger women, but historically, adherence to these evidence-based recommendations has been suboptimal. Methods To describe contemporary patterns of osteoporosis screening, we conducted a retrospective analysis using the OptumLabs™ Data Warehouse, a database of de-identified administrative claims, which […]

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Heavy Cannabis Use Is Associated With Low Bone Mineral Density and an Increased Risk of Fractures

To investigate possible associations between recreational cannabis use and bone health in humans. Methods Cross-sectional study of individuals recruited from primary care in the UK between 2011 and 2013. Cases were regular smokers of cannabis divided into moderate (n = 56) and heavy user (n = 144) subgroups depending on whether they reported fewer or more than […]

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Double Fixation: Bilateral Bisphosphonate-Related Hip Fractures

Bisphosphonates have been in use since the 1960s for the treatment of osteoporosis. They reduce bone resorption by inhibiting the action of osteoclast cells and also by inducing osteoclast apoptosis.1, 2 Since 2005, multiple studies have shown an increased prevalence of minimal-trauma subtrochanteric and diaphyseal femoral fractures in patients taking long-term bisphosphonate therapy.2, 3, 4, 5, 6, 7, 8, 9, 10 It is presumed that bisphosphonates […]

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Diuretic Use and Risk of Vertebral Fracture in Women

  Vertebral fracture is the most common type of osteoporotic fracture. While thiazide diuretics, which are commonly prescribed for the treatment of hypertension, decrease calciuria, they may also induce hyponatremia, which has been associated with increased vertebral fracture risk. Loop diuretics increase calciuria, which would reduce bone mineral density and increase vertebral fracture risk, but […]

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Vertebral Fractures: Clinical Importance and Management

  Vertebral fractures are the most common type of osteoporotic fracture and are associated with substantial morbidity and decreased survival. In the United States, annual direct management costs for vertebral fractures are more than $1 billion (United States dollars in 2011). Vertebral fracture, once suspected, can be confirmed by X-rays, computerized tomography, magnetic resonance imaging, or vertebral […]

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