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Mortality in Elderly Patients with Acute Venous Thromboembolism

  Long-term predictors and causes of death are understudied in elderly patients with acute venous thromboembolism. Methods We prospectively followed up 991 patients aged ≥65 years with acute venous thromboembolism in a multicenter Swiss cohort study. The primary outcome was overall mortality. We explored the association between patient baseline characteristics and mortality, adjusting for other […]

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Joseph S. Alpert, MD

Despite Advances, DVT Rates Remain High (video)

Despite advances in identification, prophylaxis, and treatment between 1985 and 2009, the annual event rate of venous thromboembolism has increased and remains high. Read new research in the October 2014 issue of The American Journal of Medicine.

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The Hypermetabolic Mushroom

The Hypermetabolic Mushroom: Superior Vena Cava Syndrome   Presentation A 40-year-old man, who had had a successful heart transplant, later developed a very rare and unrelated cardiac problem. He presented with progressive symptoms of cough along with cyanosis and swelling of the face and arms. On examination, he had edema of the face and upper […]

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Appropriate Use of D-dimer in Hospital Patients

D-dimer, the final product of plasmin-mediated degradation of fibrin-rich thrombi, has emerged as a simple blood test that can be used in diagnostic algorithms for the exclusion of venous thromboembolism. D-dimer also is used as a part of the diagnostic tests for disseminated intravascular coagulation, where excessive thrombin generation is the key pathophysiological factor. However, […]

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Statins Decrease the Occurrence of Venous Thromboembolism in Patients with Cancer

In addition to cholesterol-lowering effect, statins exhibit anti-thrombotic and anti-inflammatory properties, which may affect coagulation cascade. In cancer patients, the use of statins decreased the odds of developing venous thromboembolism, when compared with non-statins users. Abstract Background Recent data suggest a reduction in the occurrence of venous thromboembolism in select groups of patients who use […]

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