Tag Archives: cardiology

Short-Term Prognosis of Myocardial Injury, Type 1, and Type 2 Myocardial Infarction in the Emergency Unit

Type 2 myocardial infarction and nonischemic myocardial injury, corresponding to troponin elevation without atherothrombosis, are emerging concepts suspected of being common in emergency departments (ED). However, their respective frequencies, risk profiles, and short-term prognoses remain to be investigated. METHODS Among all the patients admitted from January 2014 to December 2016 in a university hospital ED […]

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A Reappraisal of the Lipid Hypothesis

The lipid hypothesis, which postulates that lowering serum cholesterol saves lives and prevents cardiovascular disease, has been supported by a prodigious volume of evidence over the past 30 years.1 Lowering low-density lipoprotein cholesterol (LDL-C) has become the foundation of cardiovascular disease prevention guidelines, yet not all of the evidence supports this recommendation.2 A reappraisal of the lipid […]

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Importance of Genetic Testing in the Diagnosis of Transthyretin Cardiac Amyloidosis

To the Editor: Systemic amyloidosis results from extracellular deposition of fibrillar material derived from aggregation of precursor proteins into insoluble beta-pleated sheets. The most frequently recognized types are due to prolonged inflammation, deposition of immunoglobulin light chains, and accumulation of transthyretin, a tetrameric protein synthesized in the liver. Transthyretin amyloidosis can occur owing to wild-type […]

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Clinical Features and Prognosis of Type 2 Myocardial Infarction in Acutely Decompensated Diabetic Patients

After the introduction of the universal definition of myocardial infarction, the incidence and diagnosis of type 2 myocardial infarction have risen dramatically, yet there are no clear guidelines on clinical management. Diabetic patients are at high risk for developing type 2 myocardial infarction when admitted in a decompensated state, and they are also at high […]

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man holding his chest

Do Not Resuscitate Tattoos

A recent New England Journal of Medicine letter gained national attention by describing an emergency room visit by a patient with a tattoo on his chest, “Do Not Resuscitate.” The article told how the emergency room physicians, who had not encountered this issue before, contacted their medical ethics specialists to make sure they were complying with their […]

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