Tag Archives: cardiology

Cardiovascular Risks of Exogenous Testosterone Use Among Men

We sought to evaluate whether exogenous testosterone therapy is associated with increased risk of serious cardiovascular events as compared with other treatments or placebo. Methods Study selection included randomized controlled trials (RCTs) and observational studies that enrolled men aged 18 years or older receiving exogenous testosterone for 3 or more days. The primary outcomes were […]

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Nonobstructive Hypertrophic Cardiomyopathy Out of the Shadows

Hypertrophic cardiomyopathy was first recognized as a disease of obstruction to left ventricular outflow, hence, its early names and acronyms such as idiopathic hypertrophic subaortic obstruction. The nonobstructive subset of patients, incapable of developing mechanical impedance to left ventricular outflow at rest or with physiologic exercise, was initially recognized by the Braunwald group at the […]

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Joseph S. Alpert

How Can We Improve the Management of Patients with Hypertension?

Hypertension continues to be a major health problem in the United States, affecting more than 76 million US citizens. Despite marked improvement in detection and therapy of patients with hypertension over recent decades, substantial morbidity and mortality still occur, especially in the Southeastern United States. Hypertension detection programs are common throughout the country and can […]

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Chest Pain in a 39-Year-Old Man: What Could Be the Underlying Cause?

  A 39-year-old man with unremarkable past medical history, but with a positive family history for coronary artery disease, was admitted to the hospital because of persistent arterial hypertension and sudden-onset chest pain in the mid-substernal region with neck radiation. Assessment Results from physical examination were unremarkable. The 12-lead electrocardiogram and the cardiac biomarkers were […]

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Inside Out: Bone Marrow Necrosis and Fat Embolism

  Neurologic symptoms initially attributed to infection were ultimately the result of a devastating hematologic condition. The patient, a 57-year-old woman, was rushed to the emergency department for somnolence and slurred speech. She had experienced low back pain during the preceding week. Her medical history was notable for a ventriculoperitoneal shunt placed several years ago […]

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