Tag Archives: cardiology

Importance of Genetic Testing in the Diagnosis of Transthyretin Cardiac Amyloidosis

To the Editor: Systemic amyloidosis results from extracellular deposition of fibrillar material derived from aggregation of precursor proteins into insoluble beta-pleated sheets. The most frequently recognized types are due to prolonged inflammation, deposition of immunoglobulin light chains, and accumulation of transthyretin, a tetrameric protein synthesized in the liver. Transthyretin amyloidosis can occur owing to wild-type […]

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Clinical Features and Prognosis of Type 2 Myocardial Infarction in Acutely Decompensated Diabetic Patients

After the introduction of the universal definition of myocardial infarction, the incidence and diagnosis of type 2 myocardial infarction have risen dramatically, yet there are no clear guidelines on clinical management. Diabetic patients are at high risk for developing type 2 myocardial infarction when admitted in a decompensated state, and they are also at high […]

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man holding his chest

Do Not Resuscitate Tattoos

A recent New England Journal of Medicine letter gained national attention by describing an emergency room visit by a patient with a tattoo on his chest, “Do Not Resuscitate.” The article told how the emergency room physicians, who had not encountered this issue before, contacted their medical ethics specialists to make sure they were complying with their […]

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man holding chest and woman offering him water

Oxygen Therapy in Patients with Acute Myocardial Infarction: A Systemic Review and Meta-Analysis

  Oxygen therapy is frequently used for patients with acute myocardial infarction. The aim of this study is to perform a systematic review and meta-analysis to compare the outcomes of oxygen therapy versus no oxygen therapy in post–acute myocardial infarction settings. Methods A systematic search of electronic databases was conducted for randomized studies, which reported […]

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Severe Pulmonary Alveolar Proteinosis in a Young Adult

  Pulmonary alveolar proteinosis is a rare lung disorder characterized by abnormal accumulation of surfactant within alveoli. Clinical presentation is nonspecific, but associated with characteristic radiologic findings and unique management options. We highlight a case of severe pulmonary alveolar proteinosis requiring total lung lavage in a young healthy man. Case Report A 37-year-old man with […]

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