Low cardiorespiratory fitness has been established as a risk factor for cardiovascular-related morbidity. However, research about the impact of fitness on lipid abnormalities, including atherogenic dyslipidemia, has produced mixed results. The purpose of this investigation is to examine the influence of baseline fitness and changes in fitness on the development of atherogenic dyslipidemia. Methods […]Read more
The American Journal of Medicine website has posted a new continuing medical education module on lowering cholesterol. LDL Cholesterol Lowering: How and How Low? Program Overview The latest American College of Cardiology/American Heart Association lipid management guidelines make two general statements: 1) that elevated LDL cholesterol levels should be treated with the drug class proven […]Read more
The role of low-density lipoprotein cholesterol (LDL-C) in the pathophysiology of atherosclerotic cardiovascular disease, which may present as coronary heart disease, stroke, and peripheral arterial disease, has been well documented in several studies. The decrease in LDL-C levels leads to a significant reduction in the risk of atherosclerotic cardiovascular disease. Statins have become the first line […]Read more
2013 Cholesterol Guidelines Revisited: Percent LDL Cholesterol Reduction or Attained LDL Cholesterol Level or Both for Prognosis?
The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) guideline on the treatment of blood cholesterol recommends moderate- to high-intensity statins for patients with atherosclerotic cardiovascular disease but departs from the traditional treat-to-target approach. Whether percent low-density lipoprotein cholesterol (LDL-C) reduction or attained LDL-C levels add incremental prognostic value to statin dose is not […]Read more