Tag Archives: Clinical Research
nurse pushes gurney down hospital hallway

Trends in Prolonged Hospitalizations in the United States from 2001 to 2012

Health policy debate commonly focuses on frequently hospitalized patients, but less research has examined trends in long-stay patients, despite their high cost, effect on availability of hospital beds, and physical and financial implications for patients and hospitals. Methods Using the National Inpatient Sample, a nationally representative sample of acute care hospitalizations in the US, we […]

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Smoking Cessation: The Urgent Need for Increased Utilization of Varenicline

In the US, cigarette smoking causes 480,000 premature deaths annually, due mainly to a twofold increased risk of cardiovascular disease and a 20-fold increased risk of lung cancer.1 Public health efforts and effective cessation treatments–including behavioral counseling and medications–have decreased US rates to approximately 14%; they are markedly increasing in most developing countries.2 Smoking and the emerging […]

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nurse holding hand of elderly woman patient

Dipeptidyl Peptidase-4 Inhibitors, Peripheral Arterial Disease, and Lower Extremity Amputation Risk in Diabetic Patients

Recent studies have elucidated the vascular protective effects of dipeptidyl peptidase-4 (DPP-4) inhibitors. However, to date, no large-scale studies have been carried out to determine the impact of DPP-4 inhibitors on the occurrence of peripheral arterial disease, and lower extremity amputation risk in patients with type 2 diabetes mellitus. Methods We conducted a retrospective registry […]

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30-Day Readmissions After an Acute Kidney Injury Hospitalization

The risk of hospital readmission in acute kidney injury survivors is not well understood. We estimated the proportion of acute kidney injury patients who were rehospitalized within 30 days and identified characteristics associated with hospital readmission. Methods We conducted a population-based study of patients who survived a hospitalization complicated by acute kidney injury from 2003-2013 […]

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Mortality in Elderly Patients with Acute Venous Thromboembolism

  Long-term predictors and causes of death are understudied in elderly patients with acute venous thromboembolism. Methods We prospectively followed up 991 patients aged ≥65 years with acute venous thromboembolism in a multicenter Swiss cohort study. The primary outcome was overall mortality. We explored the association between patient baseline characteristics and mortality, adjusting for other […]

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