Tag Archives: Drugs
doctor uses tablet with patient

‘Urinary Tract Infection’ and the Microbiome

The current paradigm for managing uncomplicated “urinary tract infection” (“UTI”) is deeply flawed. “UTI” is ambiguously defined, and coupled with a belief that “bacteria are not normal inhabitants of the urinary tract,”1 the diagnosis often leads to unnecessary, harmful antibiotic treatment. Although bacteriuria identified by standard clinical cultures (which we will call standard bacteriuria) is central […]

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Stubborn Creatures: Dormant Staphylococcus aureus

A healthy 70-year-old woman was admitted with a 3-day history of a pus-emitting wound on her left shin, in the absence of trauma. She was afebrile, and examination was normal excepting a warm, erythematous and tender area over her left distal tibia with a central swollen area discharging pus. Hemoglobin was 11.7 g/dL, white blood […]

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Disposing of Unused Medications: Have We Been Doing It All Wrong?

Most physicians probably give little thought to the estimated 10%-30% of medications that patients don’t end up consuming.1, 2 On the rare occasion when patients do ask their doctors where to dispose of unused medications, a physician could hardly be criticized for recommending disposal in the household garbage. Indeed, until recently, trash disposal was assumed by most […]

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Strong Man with a Weak Heart: The Ill Effects of Performance-Enhancing Drug Use

An undisclosed habit accounted for severe left ventricular dysfunction and hepatic lesions in a young bodybuilder. A 25-year-old bodybuilder with a history of liver cysts presented with a 5-day history of epigastric discomfort, nausea, vomiting, diaphoresis, and intermittent shortness of breath. The patient was not taking any prescription medications and denied use of tobacco, alcohol, […]

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Curious Crosses: Injection-Induced Lesions

Skin biopsy provided an elusive diagnosis and evidence that the patient had likely omitted important information during medical interviews. A 43-year-old man with a history of alcohol and opioid use was admitted to the inpatient ward from the infectious disease clinic. For 2 weeks, he had experienced recurrent, painful skin nodules that expressed bloody, purulent […]

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