Tag Archives: Rheumatology
Osteoporosis

Western Osteoporosis Alliance Clinical Practice Series: Evaluating the Balance of Benefits and Risks of Long-Term

Osteoporosis is a chronic disease that requires life-long strategies to reduce fracture risk. Few trials have investigated the balance of benefits and risk with long-term use of osteoporosis therapies, and fewer still have investigated the consequences of treatment discontinuation. The best available evidence suggests that up to 10 years of treatment with an oral bisphosphonate […]

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woman holding knee

Black Pump Independence

“And just why do you need this blood test?” the elderly woman demanded in her fierce quiet voice. She glared up at me past elegant, hand-drawn eyebrows. This was her third day in the hospital; my third week as an intern. We had had this conversation before. Mildred refused to allow her blood to be […]

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Joint Hypermobility Syndrome: Recognizing a Commonly Overlooked Cause of Chronic Pain

Joint hypermobility syndrome, also known as benign hypermobility syndrome, is a connective tissue disease characterized by joint instability, chronic pain, and minor skin changes. It shares many clinical features of Ehlers-Danlos syndrome, Hypermobility Type; enough so that many authorities consider them as one disease process. Approximately 3% of the general population is believed to have […]

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Looking for Sarcopenia Biomarkers

Sarcopenia, defined as age-associated loss of skeletal muscle mass and function, has emerged as an important public health issue. It is associated with higher mortality, morbidity, physical disability, and health care cost.1, 2While sarcopenia should be diagnosed with measurements of muscle mass and function, serum biomarkers are needed for screening of sarcopenia in a large population. […]

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Double Fixation: Bilateral Bisphosphonate-Related Hip Fractures

Bisphosphonates have been in use since the 1960s for the treatment of osteoporosis. They reduce bone resorption by inhibiting the action of osteoclast cells and also by inducing osteoclast apoptosis.1, 2 Since 2005, multiple studies have shown an increased prevalence of minimal-trauma subtrochanteric and diaphyseal femoral fractures in patients taking long-term bisphosphonate therapy.2, 3, 4, 5, 6, 7, 8, 9, 10 It is presumed that bisphosphonates […]

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