Tag Archives: syphilis
(A) Esophagogastroduodenoscopy demonstrated multiple ulcers in the prepyloric area of the patient's stomach. (B) This is a close-up of a prepyloric ulcer.

A Surprising Diagnosis: Syphilitic Gastritis and Hepatitis

When patients present with gastrointestinal symptoms, sexually transmitted infection is unlikely to be at the top of the differential diagnosis. A 47-year-old homosexual man underwent evaluation for persistent fatigue, abdominal pain, and anemia with a positive fecal occult stool test, all of which raised concern for an acute gastrointestinal bleed. Approximately 6 months earlier, the […]

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First Portrait of a Syphilitic Patient: Ulrich von Hutten

In current times syphilis can be considered a re-emergent sexually transmitted infection and a crucial public health problem, with a worldwide overall rate increase. In particular, in the United States a total of 27,814 cases were reported in 2016, with a rate of 8.7 cases per 100,000 population, which represents a 74.0% increase compared with […]

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Ocular fundus image of the left eye shows mild optic disc swelling, multifocal retinochoroidal exudates, retinal phlebitis, and mild vitreous opacity.

Sometimes the Eyes Say More Than the Mouth

A 48-year-old man with a history of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS)-associated cryptococcal meningitis was referred to our hospital with blurred vision in his left eye for several months. He was diagnosed with bilateral chronic posterior uveitis (Figure). After ruling out secondary uveitis, such as sarcoidosis, Behçet disease, Vogt-Koyanagi-Harada disease, […]

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The patient had a hyperpigmented maculopapular rash on his palms and the soles of his feet.

A Red Herring in the Green Grass: Syphilitic Membranous Glomerulonephritis

Physical discomfort attributed to a routine chore was actually an unusual presentation of an insidious infection. A 51-year-old man presented to the emergency department and reported 1 week of persistent, localized lower back pain that began after he had spent the day mowing his lawn. He denied any trauma, rash, dysuria, discoloration of urine, or […]

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This abdominal computed tomography coronal section demonstrates the mass's 8.5-cm cranial-caudal dimensions.

Misdirected by a Mass: Syphilis

The presence of an intraabdominal mass suggested malignancy rather than an increasingly common sexually transmitted infection. A 20-year-old man presented with fever and severe epigastric pain. Three weeks earlier, he sought treatment for a sore throat at an urgent care center. At that time, rapid strep testing was negative, and his symptoms subsequently resolved. One […]

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