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Cervical Cancer Screening: What’s New? Updates for the Busy Clinician

In the United States, 12,000 women are diagnosed with cervical cancer each year, even though the screening for this disease is safe and effective. There are 3 types of screening options available: cervical cytology (Papanicolaou or “Pap” test), Pap/HPV (human papillomavirus) co-test, and HPV-only test. With simplified options such as HPV-only screening, providers who have been […]

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Increased Vulnerability to Poorer Cancer-Specific Outcomes Following Recent Divorce

Prior studies have only considered the association between static marital status and cancer-specific outcomes. We aim to measure the effect of recent divorce on cancer-specific outcomes. Methods There were 83,804 patients with 2 malignancies, diagnosed 12 to 60 months apart, from 1973-2006 from the Surveillance, Epidemiology, and End Results database. Patients were identified as newly […]

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Senator McCain and Our Shared Humanity

  Despite our country’s political divisions, I trust we are all praying for Senator McCain as he confronts his glioblastoma diagnosis. Unfortunately, I can guess the anguish Senator McCain and his family are experiencing. My wife Carolyn, a breast cancer surgeon and a breast cancer survivor, was diagnosed with the same malignant brain tumor in […]

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Computed tomography confirmed ultrasound findings, including the presence of a mass at the head of the pancreas and pancreatic ductal dilation.

The Hyperlipidemia Effect: Pseudohyponatremia in Pancreatic Cancer

A patient’s newly discovered malignancy was evidently accompanied by a sodium deficit. The 48-year-old man presented to the Emergency Department for evaluation of abdominal pain and weight loss. He described gradual onset of severe, burning, epigastric pain with radiation to the back. In addition, he reported a 70-lb weight loss over 2 months, yellowing of […]

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The trigeminocardiac reflex pathway diagram. 1) Trigeminal ganglion via sensory fibers of trigeminal nerve. 2) Sensory nucleus of trigeminal nerve. 3) Internuncial fibers. 4) Motor nucleus of the vagus nerve. 5) Efferent vagal nerve to the heart and stomach.

Trigeminocardiac Reflex as the Presentation of Maxillary Sinus Adenocarcinoma

A 54-year-old man with history of tobacco use presented to the Emergency Department with a few-hour history of dizziness and 2-month history of intermittent right jaw pain. His blood pressure was 68/48 mm Hg, heart rate was 55 beats per minute, and oxygen saturation was 85% on room air. Physical examination was notable for a […]

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(A) Cauliflower-like lesion growing in the right nasal vestibule and occluding the naris; (B) papillary architecture with hyperkeratosis of the overlying squamous epithelium; (C) koilocytosis, which is characteristic of active viral replication; and (D) invasive carcinoma beyond the basement membrane (black arrow), consisting of irregular nests of hyperchromatic cells showing squamous differentiation and focal mitotic figures (black asterisks).

Intranasal Condyloma Acuminatum with Malignant Transformation

A 48-year-old man with a growing mass in the right naris and epistaxis for 6 months visited our department in August 2016. He had a history of diabetes mellitus and psoriasis. We observed a cauliflower-like lesion in the right nasal vestibule (Figure A), extending to the septum and nasal floor. Nasopharyngoscopy revealed that the nasopharynx, oropharynx, […]

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