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Chest radiograph at initial presentation. Cardiomegaly and moderate left pleural effusion noted.

Drugs, the Thyroid, and the Heart: A Lethal Cocktail

A 53-year-old man was referred for evaluation of a raised international normalized ratio blood result. He had been taking warfarin and amiodarone for 2 years following a transient episode of atrial fibrillation following a percutaneous coronary interventional procedure. He was receiving treatment for severe left ventricular systolic dysfunction and type 2 diabetes mellitus (Table 1). […]

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The patient also had hemorrhagic necrosis of the skin and soft tissue of the right thigh.

A Genetic Origin? Purpura Fulminans

Over days, a patient’s relatively small lesion evolved into widespread tissue damage. A previously healthy 49-year-old Arab woman was admitted for a 2-cm painful red lesion on her left breast. She had been well until a few days earlier, when she developed left flank pain and was treated with ofloxacin for a presumed urinary tract […]

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heart-ecg-background-stock

Transitional Care Interventions for Heart Failure: What Are the Mechanisms?

  Two decades ago, heart failure clinics were proposed widely as an effective means of improving care.1 Despite dozens of trials over subsequent years, it has often been difficult to ascertain the true effectiveness of such programs due to poor descriptions of study populations, interventions, comparators, and outcomes. This is compounded by the use of terms […]

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Myocardial Infarction

J. Heuser
19. June 2006

Personality Traits in Patients with Myocardial Infarction with Nonobstructive Coronary Arteries

The purpose of this study was to describe type A behavior pattern and trait anger in patients with myocardial infarction with nonobstructive coronary arteries (MINOCA) and compare them with patients with coronary heart disease and healthy controls. Type A behavior pattern and anger have been linked to coronary heart disease in previous studies. This is […]

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pregnant woman getting her blood pressure taken

High-Sensitivity Cardiac Troponin I Levels in Normal and Hypertensive Pregnancy

  The purpose of this study was to examine the association of circulating concentrations of high-sensitivity cardiac troponin I (hs-cTn) in the various trimesters of pregnancy in patients with and without hypertension. Methods This was a prospective cross-sectional study of pregnant and postnatal women aged between 18-35 years with no coexisting diseases. Serum samples were […]

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Dr. Joseph S. Alpert

Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA)

When I (JSA) first heard the term MINOCA, it made me think that perhaps it referred to an ancient civilization in Greece resembling the Minoans on Crete. For example, “Archeologists had just unearthed the remains of one of the cities of Minoca in northern Greece.” Of course, for cardiologists, MINOCA has nothing to do with ancient […]

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