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human heart with cardiogram

Net Clinical Benefit of Non-Vitamin K Antagonist vs Vitamin K Antagonist Anticoagulants in Elderly Patients with Atrial Fibrillation

The risks of thromboembolic and hemorrhagic events in patients with atrial fibrillation both increase with age; therefore, net clinical benefit analyses of anticoagulant treatments in the elderly population are crucial to guide treatment. We evaluated the 1-year clinical outcomes with non-vitamin-K antagonist and vitamin K antagonist oral anticoagulants (NOACs vs VKAs) in elderly (≥75 years) […]

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Clinical presentation patterns of AF versus likelihood of detection with monitoring. Dark bars indicate times that AF is present. AF = atrial fibrillation; ECV = elective cardioversion.

Mass Screening for Atrial Fibrillation: The Hype, The Methods, and The Application

Recently, Apple launched new heart-related features for their Apple Watch, including an app cleared by the US Food and Drug Administration that notifies wearers if atrial fibrillation has occurred. Apple admits, however, that the watch cannot detect all episodes; inconclusive results are possible; and it is not intended for people with known atrial fibrillation.1 Notably, this comes shortly […]

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Real-Life Benefits of Statins for Cardiovascular Prevention in Elderly Subjects: A Population-Based Cohort Study

The benefits of initiating statins in the elderly remains debated. We evaluated the effects of initiating statins in the elderly, according to cardiovascular risk. Methods This population-based cohort study used data of the representative sample of the French health care system database for the 2008-2015 period. New users of statins, aged 75 years and older, […]

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Pulse Pressure, Cardiovascular Events, and Intensive Blood-Pressure Lowering in the Systolic Blood Pressure Intervention Trial (SPRINT)

The efficacy and tolerability of intensive blood-pressure lowering may vary by pulse pressure (systolic minus diastolic blood pressure). Methods SPRINT randomized 9361 high-risk adults without diabetes and who were ≥50 years with systolic blood pressure 130-180 mm Hg to intensive or standard antihypertensive treatment. The primary efficacy end point was the composite of acute coronary […]

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On positron emission tomography/computed tomography, 18F-fludeoxyglucose accumulation was seen in bilateral carotid, iliac, femoral, and popliteal arteries, and thoracic aorta with standardized uptake value maximum of 6.94 in right iliac artery. Arrows (A) and arrowheads (B).

Diffuse Vascular FDG Uptake in Late Onset Takayasu Arteritis

A 75-year-old Japanese woman presented to our hospital with intermittent right neck pain and right-sided headache lasting for 3 weeks. Her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level were elevated to 100 mm/h and 2.95 mg/dL, respectively. Whole body positron emission tomography (PET) and computed tomography (CT) showed 18F-fludeoxyglucose (FDG) uptake in the bilateral […]

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(A) Twelve-lead electrocardiogram showing ST-segment elevations >2 mm in inferolateral leads caused by dissection of the distal portion of a so-called wraparound left anterior descending artery. (B) Thrombotic occlusion of the proximal left anterior descending artery, which was treated with simple angioplasty and intracoronary administration of abciximab with final Thrombolysis In Myocardial Infarction (TIMI) 1 flow. (C) Intravascular ultrasound with evidence of intramural hematoma (solid arrow), left anterior descending artery dissection (dotted arrow), and (D) control coronary angiography after 48 hours with final TIMI 3 flow.

More Martial than Arts: Coronary Artery Dissection after Chest Kick

A 40-year-old male smoker without relevant medical history reported to the Emergency Department 2 days after a kick to his unprotected chest during a karate training session. The day before, he had presented with severe chest pain and his general practitioner had prescribed ibuprofen. No electrocardiogram (ECG) had been done. At the Emergency Department, the […]

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