The American Journal of Medicine Blog

A 59-year-old woman with no prior liver disease or portal hypertension presented with an episode of right upper quadrant pain that lasted for 3 hours. The patient had a history of cholelithiasis, which was diagnosed 3 years earlier. She denied any other symptoms. Her social and family history were unremarkable. Assessment Her examination was remarkable […]

Does testosterone supplementation impact heart disease risk? The March 2017 issue of the American Journal of Medicine includes a new meta-analysis that looks at the use of testosterone supplements and cardiovascular disease risk. In this video Dr. Joseph S. Alpert talks about testosterone supplements and risk. Read the Research: Cardiovascular Risks of Exogenous Testosterone Use […]

To derive and validate a single metric of activity tracking that associates with lower risk of cardiovascular disease mortality. Methods We derived an algorithm, Personalized Activity Intelligence (PAI), using the HUNT Fitness Study (n = 4631), and validated it in the general HUNT population (n = 39,298) aged 20-74 years. The PAI was divided into three sex-specific […]

We sought to evaluate whether exogenous testosterone therapy is associated with increased risk of serious cardiovascular events as compared with other treatments or placebo. Methods Study selection included randomized controlled trials (RCTs) and observational studies that enrolled men aged 18 years or older receiving exogenous testosterone for 3 or more days. The primary outcomes were […]

Hypertrophic cardiomyopathy was first recognized as a disease of obstruction to left ventricular outflow, hence, its early names and acronyms such as idiopathic hypertrophic subaortic obstruction. The nonobstructive subset of patients, incapable of developing mechanical impedance to left ventricular outflow at rest or with physiologic exercise, was initially recognized by the Braunwald group at the […]

For centuries, the mind–body relationship has been postulated. These findings suggest that depression and anxiety are not simply “in the mind.” They are real illnesses, like any other physical illnesses, and can negatively impact the entire body, including the cardiovascular system. Despite the abundance of investigation and demonstration of a clear relationship between mental health […]