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Ocular fundus image of the left eye shows mild optic disc swelling, multifocal retinochoroidal exudates, retinal phlebitis, and mild vitreous opacity.

Sometimes the Eyes Say More Than the Mouth

A 48-year-old man with a history of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS)-associated cryptococcal meningitis was referred to our hospital with blurred vision in his left eye for several months. He was diagnosed with bilateral chronic posterior uveitis (Figure). After ruling out secondary uveitis, such as sarcoidosis, Behçet disease, Vogt-Koyanagi-Harada disease, […]

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Upper gastrointestinal study with Gastrografin (Bracco Diagnostic Inc, Monroe Township, NJ) revealed irregularity of the distal antrum in the prepyloric region and marked narrowing of the pylorus, duodenal bulb, and postbulbar duodenum (arrow).

Gastric Crohn’s Disease: A Rare Cause of Intermittent Abdominal Pain and Vomiting

Crohn’s disease is a chronic idiopathic inflammatory disease that may involve any part of the gastrointestinal tract from the mouth to the anus. It most commonly affects the terminal ileum and cecum, and less commonly is isolated to the colon. Crohn’s disease involving the stomach or duodenum is uncommon and described in only 0.5% to 4% of […]

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(A) Left temporal cutaneous lesion prior to immunotherapy. (B) Left temporal cutaneous lesion after 7 cycles of immunotherapy.

Immunotherapy in Squamous Cell Skin Carcinoma: A Game Changer?

  A 74-year-old white male was diagnosed with squamous cell carcinoma in 2013. Six months after Mohs surgery, he underwent a left superficial parotidectomy, left neck dissection, and excision of the left postauricular lymph node after confirmation of lymphatic spread. Pathology from the left parietal scalp lesion revealed multifocal invasive squamous cell carcinoma. Extranodal tumor […]

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(A, B) Axial diffusion-weighted images showed multiple areas of increased signal intensity in splenium of corpus callosum, periventricular and subcortical white matter. Apparent diffusion coefficient map is not shown but was normal.

Cerebral Fat Embolism in Hemoglobin SC Disease

A 63-year-old Caribbean man was admitted to the hospital for low back and pelvic pain. His medical history included sickle cell hemoglobin (Hb) C disease with no vaso-occlusive crisis within the last 20 years, and chronic obstructive pulmonary disease treated with inhaled corticosteroids for the last 4 years. A few hours after admission, respiratory distress […]

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(A) Transthoracic echocardiogram, parasternal long-axis view, demonstrates suggestion of a mass (arrow) adjacent to the anterior leaflet of the mitral valve. (B) Transesophageal echocardiogram, midesophageal 2-chamber view in diastole and (C) systole, clearly shows the mitral valve mass. The mass is attached to the anterior mitral leaflet, measuring 2.2 × 1.5 cm. AO = aorta; LA = left atrium; LV = left ventricle; RV = right ventricle.

What’s in a Mass?: Large Native Mitral Valve Mass

After an elective cystectomy, a 77-year-old man developed postoperative atrial fibrillation, resulting in a surprising new finding and a challenging diagnosis. He had no cardiovascular symptoms or cardiac history. The preoperative electrocardiogram was normal. Transthoracic echocardiogram identified a mass on the mitral valve (Figure 1A), new 3+ aortic valve regurgitation, and 2+ mitral valve regurgitation. Left ventricular […]

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Axillary web syndrome, with prominent cording in the involved axilla extending down into the medial forearm. This cording occurs after trauma to the lymph system and is presumed to be of lymphatic origin based on histologic and radiographic findings.

Venturing Out on a Limb: Axillary Web Syndrome

  Axillary web syndrome is a poorly understood cause of morbidity after lymph node surgery characterized by visible or palpable cords in the involved axilla extending down into the medial arm and forearm, often accompanied by a sensation of tightness, limitation of movement, and pain. Axillary web syndrome was first described in 2001 as a […]

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