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Inferior Vena Cava Filters in Patients with Recurrent Pulmonary Embolism

There are sparse data to support the recommendation for inferior vena cava (IVC) filters in patients with recurrent pulmonary embolism while on anticoagulant therapy. Methods This was a retrospective cohort study of administrative data from the Premier Healthcare Database, 2009-2014. All-cause mortality according to the use of IVC filters was evaluated in patients who suffered […]

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Spider graph to depict the effect size values on changes in health-related quality of life and its subscales and dyspnea scores from baseline to 1 year, according to percent-predicted VO2 peak <80% and >80% at 1 year. Concentric circles around the central target represent effect size in mean changes in scores from baseline to 1 year.4 Health-related quality of life and dyspnea scores improved more in patients with percent-predicted VO2 peak >80% at 1 year (distance between central point [0.0] and blue line) compared with patients with percent-predicted VO2 peak <80% at 1 year (distance between central point [0.0] and red line). PEmb-QoL = pulmonary embolism quality of life questionnaire; SF-36 = Short-Form Health Survey-36; SOBQ = University of California at San Diego Shortness of Breath Questionnaire.

Quality of Life, Dyspnea, and Functional Exercise Capacity Following a First Episode of Pulmonary Embolism

We aimed to evaluate health-related quality of life (QOL), dyspnea, and functional exercise capacity during the year following the diagnosis of a first episode of pulmonary embolism. Methods This was a prospective multicenter cohort study of 100 patients with acute pulmonary embolism recruited at 5 Canadian hospitals from 2010-2013. We measured the outcomes QOL (by […]

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Reconstruction images from CT of the abdomen and pelvis show femoral head osteonecrosis.

Inside Out: Bone Marrow Necrosis and Fat Embolism

  Neurologic symptoms initially attributed to infection were ultimately the result of a devastating hematologic condition. The patient, a 57-year-old woman, was rushed to the emergency department for somnolence and slurred speech. She had experienced low back pain during the preceding week. Her medical history was notable for a ventriculoperitoneal shunt placed several years ago […]

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Unnecessary Hospitalizations for Pulmonary Embolism: Impact on US Health Care Costs

  Each year, more than 350,000 patients are treated for pulmonary embolism in US hospitals. Recent reports indicate that the majority of these patients do not have to be hospitalized: they can be safely treated at home, which will result in a tremendous decrease in our health care costs. One of the first reports that […]

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Adherence to PIOPED II Investigators’ Recommendations for Computed Tomography Pulmonary Angiography

Non-adherence to recommendations for CT pulmonary angiography is common and exposes patients to increased risks, including potential false positive diagnoses of pulmonary embolism. Abstract  Background  Computed tomography (CT) pulmonary angiography use has increased dramatically, raising concerns for patient safety. Adherence to recommendations and guidelines may protect patients. We measured adherence to the recommendations of Prospective […]

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Robert G. Stern, MD, AJM Specialty Editor

Chasing Pulmonary Emboli

Chasing Pulmonary Emboli: Let’s Agree on One Big Thing Clinical practice guidelines can be great. It’s nice to have guidelines for the diagnosis, management, and long-term care objectives for basically every condition known to medicine. Clinical practice guidelines are supposed to be the foundation of 21st century evidence-based medicine. But clinicians frequently do not follow […]

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