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Contrast-enhanced axial slice abdominal computed tomography showing extensive peripancreatic phlegmon with abundant gas (arrows) replacing the necrotizing nonenhancing pancreatic tail. Note the normal enhancement of the pancreatic parenchyma medial to the tail.

Emphysematous Pancreatitis

A 63-year-old woman with a history of severe alcohol abuse presented with persistent abdominal pain radiating to the back, vomiting, and lassitude over a week. Examination showed tachycardia, abdominal tenderness, and bipedal edema. Abdominal ultrasound demonstrated only fatty liver. Laboratory tests were notable for white blood cell count of 16.1 × 109/L, serum albumin 1.8 g/dL, and increased […]

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smoking cigarette in the hand of young man close up

Smoking Cessation: The Urgent Need for Increased Utilization of Varenicline

In the US, cigarette smoking causes 480,000 premature deaths annually, due mainly to a twofold increased risk of cardiovascular disease and a 20-fold increased risk of lung cancer.1 Public health efforts and effective cessation treatments–including behavioral counseling and medications–have decreased US rates to approximately 14%; they are markedly increasing in most developing countries.2 Smoking and the emerging […]

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Chest x-ray image at the time of presentation to the hospital (A) and after corticosteroid therapy (C). Chest computed tomography scan at the time of presentation to the hospital (B). Representative image of cytologic findings of bronchoalveolar lavage fluid (D) (hematoxylin–eosin ×400).

Menthol-Flavored Cigarettes: Potentially a Strong Trigger of Acute Eosinophilic Pneumonia

Menthol-flavored cigarettes recently have received significant attention. Lower quit rates and higher relapse rates of smoking in people who smoke menthol-flavored cigarettes have been demonstrated.1 Additional disadvantages of menthol cigarettes also might exist. We present a lesson learned from a case we experienced: Menthol cigarette smoking might be a stronger trigger of acute eosinophilic pneumonia compared […]

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Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease

Alcohol is a leading cause of liver disease worldwide. Although alcohol abstinence is the crucial therapeutic goal for patients with alcoholic liver disease, these patients have less access to psychosocial, behavioral, and/or pharmacologic treatments for alcohol use disorder. Psychosocial and behavioral therapies include 12-step facilitation, brief interventions, cognitive behavioral therapy, and motivational enhancement therapy. In […]

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young-afr-amer-couple-drinking-wine

Red Wine Prevents the Acute Negative Vascular Effects of Smoking

Moderate consumption of red wine is associated with fewer cardiovascular events. We investigated whether red wine consumption counteracts the adverse vascular effects of cigarette smoking. Methods Participants smoked 3 cigarettes alone or after drinking a titrated volume of red wine. Clinical chemistry, blood counts, plasma cytokine enzyme-linked immunosorbent assays, immunomagnetic separation of CD14+monocytes for gene […]

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heroin, spoon, syringes

Addiction Interventions for Injection Drug Use-Associated Infective Endocarditis (video)

Injection drug use has sparked an increase in endocarditis. Patients hospitalized with injection drug use-associated infective endocarditis had high rates of readmission, recurrent infective endocarditis and death. Despite this, addiction interventions were suboptimal. In this video, Editor-in-chief Dr. Joseph Alpert and Assistant Editor Alexandra Queen discuss new research on injection drug use-associated infective endocarditis. Read […]

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