Tag Archives: Cancer
(A) This is what the patient's foot looked like during the index admission. The thickened skin denotes retention hyperkeratosis, which is a result of lymphedema. (B) Roughly 2 months after initiation of therapy with Unna boot compression, the patient reported marked improvement in pain and swelling. Hyperkeratosis remained.

Sole-Searing Pain: Classic Kaposi’s Sarcoma

To read this article in its entirety please visit our website. – This article originally appeared in the November 2017 issue of The American Journal of Medicine.

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The patient had dorsal edema and purpura on both hands.

Four Cancers and a Rash: Henoch–Schönlein Purpura

A patient who had a history of 4 primary malignancies developed a rash that is usually seen among children. The 65-year-old man presented with a 2-day history of anasarca, painless skin lesions, and new arthralgias in both hands. He had a previous diagnosis of amyotrophic dermatomyositis, and although he had none of the typical skin […]

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Histology confirmed the diagnosis of papillary urothelial carcinoma of the bladder with expression of human chorionic gonadotropin (hCG) [(A) Papillary urothelial carcinoma pTaG1, hematoxylin and eosin (H&E), 200×; (B) Distribution of hCG-expressing urothelial cells: irregular and focal expression, immunohistochemical stain (brown) for β-hCG, 300×; (C) Expression of hCG in urothelial carcinoma cells: intracytoplasmic and intranuclear expression, immunohistochemical stain for β-hCG, 400×].

Gynecomastia: Look Beyond the Obvious

A 29-year-old man was referred to our clinic with a 4-week history of a tender predominant left breast enlargement without nipple discharge. He had been practicing bodybuilding regularly for years, but denied taking anabolic androgenic steroids. His past medical history was unremarkable apart from surgical treatment of undescended testes in childhood. His sexual desire and […]

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detail of cancer cell

Hepatocellular Carcinoma Screening Associated with Early Tumor Detection and Improved Survival Among Patients with Cirrhosis in the US

Professional societies recommend hepatocellular carcinoma screening in patients with cirrhosis, but high-quality data evaluating its effectiveness to improve early tumor detection and survival in “real world” clinical practice are needed. We aim to characterize the association between hepatocellular carcinoma screening and early tumor detection, curative treatment, and overall survival among patients with cirrhosis. Methods We […]

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Portable chest x-ray on presentation (A) and follow-up computed tomography of the chest without contrast (B).

Not Just Skin Deep: Distant Metastases from Cutaneous Squamous Cell Carcinoma

  Cutaneous squamous cell carcinoma is the second most common cancer in the United States and has 5-year recurrence and metastasis rates of 8% and 5%, respectively.1, 2 However, not all cutaneous squamous cell carcinomas are alike, and the size and location of the primary lesion confers a widely variable risk for recurrence and metastasis. Case Summary […]

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The lower panel demonstrates the lesion in the supraclavicular area on conventional ultrasonography. Encapsulated cystic lesion with hyperechogenic areas inside being in constant movement. The upper panel shows largely decreased elasticity of the peripheral part of the lesion on sonoelastographic examination.

Subcutaneous Lesion in an Oncologic Patient

A 40-year-old Caucasian woman presented to our university hospital after she noticed a mass in the right supraclavicular area. The lump was easily palpable, sized 1-1.5 cm, firm, and rather immovable, with surrounding edema (Figure 1). She had noticed the lesion approximately 2 weeks earlier, and during that time the mass was gradually enlarging. Her personal […]

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