Tag Archives: Coronary Artery Disease
Antithrombotic strategy by CHA2DS2-VASc score. DAP = dual antithrombotic therapy with 2 antiplatelet agents; OAC + AA = dual antithrombotic therapy with an oral anticoagulant plus 1 antiplatelet agent; TT = triple antithrombotic therapy (oral anticoagulation plus dual antiplatelet therapy).

Triple vs Dual Antithrombotic Therapy in Patients with AF & CAD

Background The role of triple antithrombotic therapy vs dual antithrombotic therapy in patients with both atrial fibrillation and coronary artery disease remains unclear. This study explores the differences in treatment practices and outcomes between triple antithrombotic therapy and dual antithrombotic therapy in patients with atrial fibrillation and coronary artery disease. Methods Using the Outcomes Registry […]

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Computed tomography scan of the chest in a 59-year-old woman on warfarin. This patient had a longstanding history of pulmonary embolism and no other vascular risk factors and had been treated with warfarin for 30 years. This scan shows significant calcification of the left anterior descending artery and the left and right bronchi.

Warfarin and Vascular Calcification

  The vitamin K antagonist, warfarin, is the most commonly prescribed oral anticoagulant. Use of warfarin is associated with an increase in systemic calcification, including in the coronary and peripheral vasculature. This increase in vascular calcification is due to inhibition of the enzyme matrix gamma-carboxyglutamate Gla protein (MGP). MGP is a vitamin K-dependent protein that […]

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Coronary angiography images demonstrating severe ostial stenosis of the intermediate artery (A) treated successfully by coronary stenting (B). ECG demonstrating global ‘saddle shaped’ ST elevation consistent with pericarditis (C). Chest radiography showing bilateral pleural effusion (D).

Postcardiac Injury Syndrome: A Rare Complication of Elective Coronary Angioplasty

Postcardiac injury syndrome conventionally has been described after myocardial infarction or cardiac surgery, but it is an infrequent complication of endovascular procedures. We report an unusual case of postcardiac injury syndrome occurring immediately after elective angioplasty. A 58-year-old man attended our hospital (Northwick Park Hospital) for elective angiography for symptoms of exertional angina. He had […]

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blood pressure cuff

Treatment of Hypertension in Patients with Coronary Artery Disease.

The 2015 American Heart Association/American College of Cardiology/American Society of Hypertension Scientific Statement “Treatment of Hypertension in Patients with Coronary Artery Disease” is summarized in the context of a clinical case. The Statement deals with target blood pressures, and the optimal agents for the treatment of hypertension in patients with stable angina, in acute coronary […]

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Insidious: Takayasu Arteritis

Hypertensive crisis in a 39-year-old Haitian woman with a history of hypertension proved secondary to an underlying chronic disease. Having arrived in the emergency department for evaluation of a severe headache and shortness of breath, she added that, for several months, she had been experiencing chest pain, both at rest and with exertion. Episodes lasted […]

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T2-weighted imaging demonstrating an abnormal increase in signal suggestive of myocardial edema in the inferior and inferolateral walls.

Chest Pain and Elevated Troponins in a Patient with Prior Coronary Artery Disease: A Diagnostic Dilemma

More than one quarter of patients hospitalized with congestive heart failure are readmitted within 30 days of discharge, with total annual costs surpassing $20 billion. In patients presenting with acute heart failure symptoms and chest pain, differentiating acute coronary syndrome from acute myocarditis is challenging. Newer imaging modalities, such as cardiac magnetic resonance imaging, can […]

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