Tag Archives: Dermatology
Raised nodular lesions on patient's shins at presentation.

Nodular Thyroid Dermopathy: Not a Hallmark of Graves Disease

  A 40-year-old man presented to the outpatient department with complaints of multiple, nontender, raised nodular lesions on his shins bilaterally for the past year (Figure 1). The lesions had an insidious onset and were progressively increasing in size. He was evaluated at an outside clinic. Biopsy was performed multiple times, and possibility of spindle […]

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The patient also had hemorrhagic necrosis of the skin and soft tissue of the right thigh.

A Genetic Origin? Purpura Fulminans

Over days, a patient’s relatively small lesion evolved into widespread tissue damage. A previously healthy 49-year-old Arab woman was admitted for a 2-cm painful red lesion on her left breast. She had been well until a few days earlier, when she developed left flank pain and was treated with ofloxacin for a presumed urinary tract […]

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A Bad Sign: Dermatomyositis with Interstitial Lung Disease

The presence of an autoantibody explained why a patient with dermatomyositis had respiratory symptoms. A 52-year-old man presented with a 1-month history of fever and rash, and a 2-week history of muscle pain and muscle weakness, which made it difficult for him to rise from a sitting position. The patient denied being a smoker or […]

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Erythematous plaques with thick, micaceous scale on the extensor lower leg of a man with plaque psoriasis.

Psoriasis and Psoriatic Spectrum Disease: A Primer for the Primary Care Physician

Psoriasis is a chronic, immune-mediated disorder with cutaneous, articular, and systemic manifestations that are associated with significant morbidity.1 The burden of disease is directly related to its prevalence, which ranges from 0.5%-11.4% in adults and 0%-1.4% in children worldwide.2 In the United States alone, approximately 7.4 million individuals have psoriasis,3 and both the incidence and prevalence of psoriasis […]

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Thinning of the hair in the frontoparietal scalp was due to androgenic alopecia.

At the Root: Cutaneous Langerhans Cell Histiocytosis

Hair loss is of deep concern to patients, mainly because of its effect on appearance. On rare occasions, however, areas of balding can signal malignancy. A 33-year-old woman was referred to our dermatology clinic because of a 15-year history of scalp eruption accompanied by intense itching and progressive hair loss. Previously, she was diagnosed with […]

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(A) Skin impairment. Papulonodular skin lesions on the tip of the nose, from 3 to 10 mm, characteristic of sarcoidosis: firm, nonedematous, noninflammatory, nonpainful, nonpruriginous, with predominant facial involvement. (B) Endoscopic view (right nasal fossa) showing a major mucosae thickening. (C) Numerous uniform circumscribed nests of non-caseating granulomata which are characterized by the paucicity of lymphocytes and absence of necrosis.

Skin and Nasal Involvement: Look for Sarcoidosis!

  Sarcoidosis is a systemic, noncaseating, granulomatous disease affecting young adults between the ages of 25 and 40 years, most often of Black origin (35.5/100,000 vs 10.9 in the White population). Although the lower respiratory tract is affected in 90% of cases, ear, nose, and throat locations are very uncommon, with a prevalence varying between […]

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