Tag Archives: diagnosis
Magnetic resonance imaging brain lesions typical of multiple sclerosis.

Multiple Sclerosis Re-Examined: Essential and Emerging Clinical Concepts

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by exacerbations of neurological dysfunction due to inflammatory demyelination. Neurologic symptoms typically present in young adulthood and vary based on the site of inflammation, although weakness, sensory impairment, brainstem dysfunction, and vision loss are common. MS occurs more frequently in women […]

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Increased Vulnerability to Poorer Cancer-Specific Outcomes Following Recent Divorce

Prior studies have only considered the association between static marital status and cancer-specific outcomes. We aim to measure the effect of recent divorce on cancer-specific outcomes. Methods There were 83,804 patients with 2 malignancies, diagnosed 12 to 60 months apart, from 1973-2006 from the Surveillance, Epidemiology, and End Results database. Patients were identified as newly […]

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The patient had multiple telangiectasias. (A) These were evident on the fingertips. (B) The oral mucosa was also affected.

Site-Seeing: Hereditary Hemorrhagic Telangiectasia with Native-Valve Endocarditis

A 69-year-old Japanese man had 2 disparate illnesses with a comparable sign. The first, an undiagnosed genetic disease, made him more susceptible to the second. He was admitted to our hospital after reporting a 1-month history of chills, malaise, anorexia, pain in the left knee, and blurred vision in the right eye. He denied urinary […]

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Dorsum of tongue showing erythematous patches with white borders (black arrows).

Geographic Tongue

A 45-year-old female patient presented to our clinic with a painless, erythematous lesion on her tongue. Medical history was negative, with absence of any allergies or habits. The patient recalled that she had a similar lesion on her tongue 6 months earlier, which resolved spontaneously. Clinical examination of the dorsal surface of the tongue revealed […]

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The trigeminocardiac reflex pathway diagram. 1) Trigeminal ganglion via sensory fibers of trigeminal nerve. 2) Sensory nucleus of trigeminal nerve. 3) Internuncial fibers. 4) Motor nucleus of the vagus nerve. 5) Efferent vagal nerve to the heart and stomach.

Trigeminocardiac Reflex as the Presentation of Maxillary Sinus Adenocarcinoma

A 54-year-old man with history of tobacco use presented to the Emergency Department with a few-hour history of dizziness and 2-month history of intermittent right jaw pain. His blood pressure was 68/48 mm Hg, heart rate was 55 beats per minute, and oxygen saturation was 85% on room air. Physical examination was notable for a […]

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cartoon of wheat in red x over stomach

Delay in Diagnosis of Celiac Disease in Patients Without Gastrointestinal Complaints

The purpose of our study is to investigate the delay in diagnosis of patients with biopsy-proven celiac disease in those who present with gastrointestinal complaints vs nongastrointestinal complaints at our tertiary care center. Celiac disease is an autoimmune disorder that affects approximately 1% of the population worldwide. Celiac disease can have variable clinical presentations; it […]

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