Tag Archives: Hypertension
The association between body mass index and efficacy and safety endpoints. The solid lines represent the incidence ratio (per 100 person-years) at each body mass index interval. The dashed lines represent the upper and lower bounds of the 95% confidence interval. The bars represent the distribution of body mass index values. The P values are for unadjusted trends.

Body Mass Index, Intensive Blood Pressure Management, and Cardiovascular Events in the SPRINT Trial

It is unclear whether intensive blood pressure management is well-tolerated and affects risk uniformly across the body mass index (BMI) spectrum. Methods The randomized, controlled Systolic Blood Pressure Intervention Trial (SPRINT) included 9361 individuals ≥50 years of age at high cardiovascular risk, without diabetes mellitus, with systolic blood pressure between 130 and 180 mmHg. Participants […]

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Pulse Pressure, Cardiovascular Events, and Intensive Blood-Pressure Lowering in the Systolic Blood Pressure Intervention Trial (SPRINT)

The efficacy and tolerability of intensive blood-pressure lowering may vary by pulse pressure (systolic minus diastolic blood pressure). Methods SPRINT randomized 9361 high-risk adults without diabetes and who were ≥50 years with systolic blood pressure 130-180 mm Hg to intensive or standard antihypertensive treatment. The primary efficacy end point was the composite of acute coronary […]

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pregnant woman getting her blood pressure taken

High-Sensitivity Cardiac Troponin I Levels in Normal and Hypertensive Pregnancy

  The purpose of this study was to examine the association of circulating concentrations of high-sensitivity cardiac troponin I (hs-cTn) in the various trimesters of pregnancy in patients with and without hypertension. Methods This was a prospective cross-sectional study of pregnant and postnatal women aged between 18-35 years with no coexisting diseases. Serum samples were […]

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When Guidelines Cause Hypertension

The 2017 ACC/AHA Hypertension Guidelines1 lowered the threshold for diagnosing hypertension from a blood pressure of ≥140/90 mm Hg to ≥130/80 mm Hg. In the United States, this effectively increases the number of adults diagnosed as “hypertensive” from 72 to 103 million.2 It has been stated that “by reclassifying people formerly considered to have pre-hypertension as having hypertension, […]

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Optimal Systolic Blood Pressure Target in Resistant and Non-Resistant Hypertension

Prior studies suggest benefits of blood pressure lowering on cardiovascular risk may be attenuated in patients with resistant hypertension compared with the general hypertensive population, but prospective data are lacking. Methods We assessed intensive (<120 mm Hg) versus standard (<140 mm Hg) systolic blood pressure targets on adverse outcome risk according to baseline resistant hypertension […]

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Dairy Consumption and 24-Hour Blood Pressure in Older Adults with Hypertension (video)

The aim was to examine the association between habitual consumption of dairy products and 24-hour ambulatory blood pressure monitoring among older adults with hypertension. Methods We conducted an analysis of 715 community-living hypertensive adults age ≥60. Habitual dairy consumption was assessed with a validated diet history. Blood pressure was recorded by 24-hour ambulatory blood pressure […]

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