Tag Archives: Infectious disease
Koplik's spots on the buccal mucosa. Measles was later confirmed by testing with anti-measles immunoglobulin-M antibodies.

Koplik’s Spots and Measles

To the Editor: Measles, one of the most transmissible diseases, is most contagious before rash manifestation. Search for the pathognomonic Koplik’s spots could be critical for the early diagnosis in this prodromal period. Case Description A 47-year-old man had high-grade fever with a peak temperature of 39.7°C, photophobia, rhinitis, and dry cough. On the fifth […]

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Ixodes scapularis, the primary vector of Lyme disease in eastern North America. (Image Credit: Public Library of Science, Wiki CC License.)

Straight Talk About Chronic Lyme Disease

Four years ago, we noted an example of irresponsible reporting on Lyme disease by an investigative television news team.1 Consequently, when we learned that this same group was airing a new 5-part series entitled, “The Lyme Wars: Investigating a Public Health Crisis,” we were most interested to see if they had done a better job this […]

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After the patient completed antibiotic therapy for ecthyma gangrenosum, the characteristic eschar remained a while longer.

One Thing after Another: Ecthyma Gangrenosum

Chronic high-dosage steroid therapy can pose a significant risk factor for infection due to its immunosuppressive effect. A 70-year-old African American man presented with acute bilateral painless vision loss. An investigative work-up produced a positive antinuclear antibody titer of 1:1280 with a speckled pattern, a positive test for anti-Ro/anti-Sjögren’s-syndrome-related antigen A antibody, and an erythrocyte […]

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Top left: High-power (oil immersion lens ×1000) peripheral smear showing atypical lymphocytes and no platelets. Top right: Low-power (×200) peripheral smear showing no platelets. Bottom: Computed tomography of the abdomen without contrast showing absence of splenomegaly or other abnormalities.

Platelet Count of Zero: A Curious Case of Thrombocytopenia

To read this article in its entirety please visit our website. -Patrick Twohig, MD, MPH, Jaclyn Rivington, MD This article originally appeared in the November 2017 issue of The American Journal of Medicine.

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Segmental muscle atrophy and fatty change. (A) Significant muscular atrophy in the right iliopsoas (green arrow). (B) Both biceps femoris (red arrow) are preserved, but other muscles are obviously atrophic with fatty change (yellow arrow).

Post-Polio-Like Syndrome

  Post-polio syndrome is a motor neuron disease that occurs in 15%-80% of patients with a history of polio.1 The diagnostic criteria for post-polio syndrome include a confirmed history of polio, partial or complete neurologic and functional recovery after acute polio, a period of more than 15 years with neurologic and functional stability, new symptoms that […]

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Chest x-ray film revealing marked cardiomegaly.

Case of Tuberculous Pericarditis Mimicking Lupus Carditis

A 48-year-old man presented to the emergency department of our hospital complaining of sharp substernal chest pain, fever, and chills for 3 days. He denied shortness of breath, cough, night sweats, nausea, vomiting, or diarrhea. He also denied dry eyes, dry mouth, oral ulcers, or photosensitivity. He was born in the Dominican Republic but has […]

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