Tag Archives: Rheumatology
A, Single variably hypopigmented papule over the left upper eye. B, Multiple hyperpigmented maculopapular rash over the neck. C, Magnetic resonance imaging of the lumbosacral spine reveals a mottled appearance of the bone marrow on the T1-weighted images. D, CT scan of the chest reveals multiple scattered nodules over both lung fields uniformly distributed without any zonal preference. E, Multiple similar-appearing noncaseating epithelioid granulomas were observed on bone marrow biopsy.

The Great Masquerader Strikes Again!

To the Editor: A 42-year-old man presented with symptoms of severe low-back pain that was aggravated by activity and bending. He also reported sharp pains radiating down the back of the right thigh. In addition, he had an occasional mild cough with yellowish-gray sputum production. He denied any weight loss, night sweats, fevers, or chills. […]

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Osteoporosis

Western Osteoporosis Alliance Clinical Practice Series: Evaluating the Balance of Benefits and Risks of Long-Term

Osteoporosis is a chronic disease that requires life-long strategies to reduce fracture risk. Few trials have investigated the balance of benefits and risk with long-term use of osteoporosis therapies, and fewer still have investigated the consequences of treatment discontinuation. The best available evidence suggests that up to 10 years of treatment with an oral bisphosphonate […]

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woman holding knee

Black Pump Independence

“And just why do you need this blood test?” the elderly woman demanded in her fierce quiet voice. She glared up at me past elegant, hand-drawn eyebrows. This was her third day in the hospital; my third week as an intern. We had had this conversation before. Mildred refused to allow her blood to be […]

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Maneuvers used to calculate the Beighton Score. The Beighton Score is calculated by adding the points obtained through each maneuvers, yielding a total maximum score of 9. A Beighton Score of 4 or higher is a major criterion for the Brighton Criteria

Joint Hypermobility Syndrome: Recognizing a Commonly Overlooked Cause of Chronic Pain

Joint hypermobility syndrome, also known as benign hypermobility syndrome, is a connective tissue disease characterized by joint instability, chronic pain, and minor skin changes. It shares many clinical features of Ehlers-Danlos syndrome, Hypermobility Type; enough so that many authorities consider them as one disease process. Approximately 3% of the general population is believed to have […]

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bone stock

Looking for Sarcopenia Biomarkers

Sarcopenia, defined as age-associated loss of skeletal muscle mass and function, has emerged as an important public health issue. It is associated with higher mortality, morbidity, physical disability, and health care cost.1, 2While sarcopenia should be diagnosed with measurements of muscle mass and function, serum biomarkers are needed for screening of sarcopenia in a large population. […]

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Pelvis anterior–posterior plain film demonstrates a right subtrochanteric hip fracture (hollow arrow) with a transverse orientation and lateral cortical thickening. Also note characteristic beaking of the contralateral left lateral femoral cortex (white arrow).

Double Fixation: Bilateral Bisphosphonate-Related Hip Fractures

Bisphosphonates have been in use since the 1960s for the treatment of osteoporosis. They reduce bone resorption by inhibiting the action of osteoclast cells and also by inducing osteoclast apoptosis.1, 2 Since 2005, multiple studies have shown an increased prevalence of minimal-trauma subtrochanteric and diaphyseal femoral fractures in patients taking long-term bisphosphonate therapy.2, 3, 4, 5, 6, 7, 8, 9, 10 It is presumed that bisphosphonates […]

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