Tag Archives: thrombosis
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National and Regional Trends in Deep Vein Thrombosis Hospitalization Rates, Discharge Disposition, and Outcomes for Medicare Beneficiaries

Older adults are at increased risk of developing deep vein thrombosis. Little is known about national trends of deep vein thrombosis hospitalizations in the context of primary and secondary prevention efforts. Methods Medicare standard analytic files were analyzed from 2015-2017 to identify Fee-For-Service patients aged ≥65 years who had a principal discharge diagnosis for deep […]

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Effectiveness and Safety of Rivaroxaban Versus Warfarin in Frail Patients with Venous Thromboembolism (video)

Frailty predicts poorer outcomes in patients receiving anticoagulation. We assessed the effectiveness and safety of rivaroxaban vs warfarin in frail patients experiencing venous thromboembolism. Methods Using US MarketScan claims data from January 2012-December 2016, we identified frail patients (using the Johns Hopkins Claims-Based Frailty Indicator score) who had ≥1 primary hospitalization/emergency department visit diagnosis codes […]

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Histopathologic example of segmental arterial mediolysis. (A, B) Microscopic evaluation of an affected mesenteric artery with linear fibrin deposition at the adventitial–medial junction, medial gaps, and dissecting pseudoaneurysms. (C, D) At increased magnification, vacuolar degeneration of medial smooth muscle can be visualized. (A, C: hematoxylin and eosin stain; B, D: elastic van Gieson stain). Bars = 300 µm (A, B) and 100 µm (C, D). Reprinted from Tyler Hall E, Gibson BA, Hennemeyer CT, Devis P, Black S, Larsen BT. Segmental arterial mediolysis and fibromuscular dysplasia: what comes first, the chicken or the egg? Cardiovascular Pathology 2016;25(2):113-115, with permission from Elsevier.

Segmental Arterial Mediolysis: An Important but Often Overlooked Cause of Multi-Vessel Thrombosis

A 52-year-old man with a past medical history significant for hypercholesterolemia and systemic hypertension presented to an outside hospital with acute-onset, diffuse abdominal and bilateral flank pain without fever, constitutional symptoms of infection, or vomiting. On physical examination, abdominal tenderness was present, but abdominal guarding, peritoneal signs, and costovertebral angle tenderness were absent. Computed tomography […]

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Prominent superficial veins over the right upper arm and shoulder, reflective of Urschel's sign.

Urschel’s Sign in Paget Schroetter Syndrome

A 32-year-old man, employed as a deckhand, was referred for right upper extremity swelling and pain of 3 months’ duration. Physical examination revealed swelling of the right upper extremity and prominent superficial veins over the right upper arm and shoulder (Urschel’s sign; Figure). Blood work including thrombophilia screen was unremarkable. Right upper extremity venous duplex ultrasonography […]

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