American Journal of Medicine, internal medicine, medicine, health, healthy lifestyles, cancer, heart disease, drugs
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Serum Insulin and Cognitive Performance in Older Adults: A Longitudinal Study

The aim of this study was to examine the association of serum glucose, insulin, and insulin resistance with cognitive functioning 7 years later in a longitudinal population-based study of Finnish older adults. Methods Serum glucose and insulin were measured at baseline in 269 dementia-free individuals aged 65-79 years, from the Cardiovascular Risk Factors, Aging, and […]

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High-Sensitivity Cardiac Troponin I Levels in Normal and Hypertensive Pregnancy

  The purpose of this study was to examine the association of circulating concentrations of high-sensitivity cardiac troponin I (hs-cTn) in the various trimesters of pregnancy in patients with and without hypertension. Methods This was a prospective cross-sectional study of pregnant and postnatal women aged between 18-35 years with no coexisting diseases. Serum samples were […]

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Burn Bright I: Reflections on the Burnout Epidemic (Part One of a Two-Part Series)

I’m not alone in having experienced burnout and its consequences. One of the hardest working and most successful in my medical school class, I experienced early predictors of later struggles: I would get anxious whenever I had to go on away rotations, partly because of being far from my family, friends, and community support network […]

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Asking How Our Patients Understand Addiction

When the President’s Commission on Combating Drug Addiction and the Opioid Crisis declares “addiction [a] chronic relapsing disease of the brain”1 and calls for expanded access to care, within those statements is recognition of the influx of patients with addiction into general medicine settings for chronic disease management. The initial conversations that can shape a patient’s […]

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Parental Leave in Graduate Medical Education: Recommendations for Reform

Becoming a new parent during residency or fellowship training is challenging and may adversely affect attainment of professional goals or even guide career specialty choice based on perceived work–life balance.1 The increase of female medical students in US medical schools to approximately 50% of graduates parallels the increase in pregnancies among females during graduate medical education […]

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Sleep Disorders

Sleep disorders are frequent and can have serious consequences on patients’ health and quality of life. While some sleep disorders are more challenging to treat, most can be easily managed with adequate interventions. We review the main diagnostic features of 6 major sleep disorders (insomnia, circadian rhythm disorders, sleep-disordered breathing, hypersomnia/narcolepsy, parasomnias, and restless legs […]

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Cannabis Legalization Does Not Influence Patient Compliance with Opioid Therapy

Prescription opioid use and opioid related deaths continue to increase nationwide. Several states have adopted legislation allowing for recreational use of cannabis. Little is known about how recreational cannabis laws impact compliance in chronic pain patients who have been prescribed opioid therapy. The goals of this study were to (1) retrospectively assess the effect of cannabis […]

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Marijuana’s Effects on Brain Structure and Function: What Do We Know and What Should We Do? A Brief Review and Commentary

The present epidemic of opioid addiction and the enthusiasm about marijuana use by advocates of its legalization may have diverted attention from its reported adverse health effects. These include clinical studies that demonstrate chronic marijuana use is associated with long-term deleterious effects on cognition.1 Neuroscientists have been carefully pairing neurodiagnostic tools with newer neuroimaging technologies to […]

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Dr. Joseph S. Alpert

Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA)

When I (JSA) first heard the term MINOCA, it made me think that perhaps it referred to an ancient civilization in Greece resembling the Minoans on Crete. For example, “Archeologists had just unearthed the remains of one of the cities of Minoca in northern Greece.” Of course, for cardiologists, MINOCA has nothing to do with ancient […]

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