Are there sex differences in presentation with myocardial infarction? Yes … but there is also significant overlap in symptoms. According to AJM Editor-in-Chief Joseph S. Alpert, this new study revealed that there are many ways that people present with a heart attack. He suggests taking a careful history and thinking about all of the options before jumping to conclusions. You can read “Sex Differences in Symptom Phenotypes Among Older Patients with Acute Myocardial Infarction” by Brush et al in the March 2022 issue of AJM on our website amjmed.com.