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Cholesterol
What's New from AJM
A Reappraisal of the Lipid Hypothesis
The lipid hypothesis, which postulates that lowering serum cholesterol saves lives and prevents cardiovascular disease, has been supported by a prodigious volume of evidence over the past 30 years.1Â Lowering low-density lipoprotein cholesterol (LDL-C) has become the foundation of cardiovascular disease prevention guidelines, yet not all of the evidence supports this recommendation.2Â A reappraisal of the lipid hypothesis may hold the...