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Aphthous Stomatitis in a Man with Psoriatic Arthritis

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A 57-year-old man was admitted to the Department of Internal Medicine for a painful aphthous stomatitis, which had been present for 2 weeks and had not resolved under antibiotic treatment (amoxicillin-clavulanic acid). He had a medical history of psoriatic arthritis, successfully treated for 5 years with adalimumab, an anti-tumor necrosis factor agent. A loss of effect had been suspected...