Chronic Lyme disease is a controversial topic in medicine. In the April 2022 issue of the American Journal of Medicine, new clinical research reported on follow-up with patients who had long-term symptoms. Most had new or pre-existing medical conditions that accounted for their symptoms, according to AJM Editor-in-Chief Joseph S. Alpert, MD, in this video. You can read “Mistaken Identity: Many Diagnoses Are Frequently Misattributed to Lyme Disease” by Kobayashi et al on our website amjmed.com.