This study looks at 19-year trends in mortality in patients hospitalized in the US with high-risk pulmonary embolism (PE). The good news is: mortality from PE has decreased. The not-so-good news is: the decrease is due to better treatment of patients with shock and with cardiac arrest, not advances in therapy for PE. AJM Editor-in-Chief Joseph S. Alpert MD discusses the research in this video. You can read “Nineteen-year Trends in Mortality of Patients Hospitalized in the United States with High-Risk Pulmonary Embolism” by Stein et. al in the October 2021 issue of the American Journal of Medicine, available at amjmed.com.