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Optimal Systolic Blood Pressure Target in Resistant and Non-Resistant Hypertension

Prior studies suggest benefits of blood pressure lowering on cardiovascular risk may be attenuated in patients with resistant hypertension compared with the general hypertensive population, but prospective data are lacking. Methods We assessed intensive (<120 mm Hg) versus standard (<140 mm Hg) systolic blood pressure targets on adverse outcome risk according to baseline resistant hypertension […]

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The Burden of Modifiable Risk Factors in Newly Defined Categories of Blood Pressure

The 2017 American College of Cardiology/American Heart Association Guideline introduced new categories of high blood pressure. The vast majority of individuals in these newly defined categories are recommended for nonpharmacological intervention rather than antihypertensive therapy. This study sought to determine the burden of potentially modifiable risk factors of hypertension among untreated adults in the newly […]

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Is Salt a Culprit or an Innocent Bystander in Hypertension? A Hypothesis Challenging the Ancient Paradigm

For decades the notion that an excessive consumption of salt (NaCl) leads to hypertension has persisted. However, this idea is based on opinion, not scientific proof. Despite this, every health organization, agency, and clinicians around the world have been advising salt restriction, especially to hypertensive patients. The present review article suggests that the consumption of […]

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Longitudinal Patterns of Cardiorespiratory Fitness Predict the Development of Hypertension Among Men and Women

Most of the existing literature has linked a baseline cardiorespiratory fitness or change between baseline and one follow-up measurement of cardiorespiratory fitness to hypertension. The purpose of the study is to assess the association between longitudinal patterns of cardiorespiratory fitness changes with time and incident hypertension in adult men and women. Methods Participants were aged […]

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Linear petechial streaks in the blood pressure cuff distribution, known as the Rumpel-Leede sign.

Capillary Fragility in Zika Virus Infection

  A 42-year-old Hispanic woman with no known medical history presented to the hospital with subjective fevers, rash, and arthralgias 5 days after returning to the US from Honduras. She reported multiple mosquito bites while abroad and noted that many relatives had similar symptoms over the preceding weeks. On arrival to the Emergency Department, her […]

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Outcomes with Other Antihypertensive Agents

Outcomes with Angiotensin-converting Enzyme Inhibitors vs Other Antihypertensive Agents in Hypertensive Blacks: Among hypertensive blacks, angiotensin-converting enzyme inhibitors were associated with a higher risk of cardiovascular events, when compared with calcium channel blockers or thiazide diuretics. Background Angiotensin-converting enzyme inhibitors are used widely in the treatment of patients with hypertension. However, their efficacy in hypertensive […]

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