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Clostridium difficile
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Appropriate Use of Proton Pump Inhibitors: A Double-Edged Sword
We read with great interest the article published by Wombell et al in the current issue of The American Journal of Medicine. The authors summarize the evidence linking proton pump inhibitors (PPIs) to hospital-acquired Clostridium difficile infection.1 They also provide a description of the possible mechanisms responsible for this association. We commend the authors for their timely contribution to the literature and wish to...